The concept of strain in organic compounds is as old as modern organic chemistry and was
initially introduced to justify the synthetic setbacks along the synthesis of small ring systems …

Chiral transition metal catalysts represent a powerful and economic tool for implementing
stereocenters in organic synthesis, with the metal center providing a strong chemical …

We report the use of photocatalysis for the homolytic ring-opening of carbonyl
cyclopropanes. In contrast to previous studies, our approach does not require a metal …

In recent years, visible light-induced transition metal catalysis has emerged as a new
paradigm in organic photocatalysis, which has led to the discovery of unprecedented …

Asymmetric catalysis is a major theme of research in contemporary synthetic organic
chemistry. The discovery of general strategies for highly enantioselective photochemical …

Ring structures such as pyridine, cyclopentane or their combinations are important motifs in
bioactive molecules. In contrast to previous cycloaddition reactions that necessitated a …

This review describes the development of enantioselective methods for the ring opening of
cyclopropanes. Both approaches based on the reaction of nonchiral cyclopropanes and …

The late stage functionalization (LSF) of complex biorelevant compounds is a powerful tool
to speed up the identification of structure–activity relationships (SARs) and to optimize …

Saturated bicycles are becoming ever more important in the design and development of new
pharmaceuticals. Here a new strategy for the synthesis of bicyclo [2.1. 1] hexanes is …

Photocatalysis opens up a new window for carbonyl chemistry. Despite a multitude of
photochemical reactions of carbonyl compounds, visible light-induced catalytic asymmetric …