Successful subversion of translation initiation factors eIF4E determines the infection success
of potyviruses, the largest group of viruses affecting plants. In the natural variability of many …

The discovery that extracellular vesicles (EVs) serve as carriers of virus particles calls for a
reevaluation of the release strategies of non-enveloped viruses. Little is currently known …

Subcellular fractionation in combination with mass spectrometry–based proteomics is a
powerful tool to study localization of key proteins in health and disease. Here we offered a …

ABSTRACT Enteroviruses (EVs)—positive-sense single-strand RNA viruses of
Picornaviridae—are among the most common human viral pathogens. Unlike other …

Enteroviruses dramatically remodel the cellular infrastructure for efficient replication and
curtailing host antiviral responses. Proteases 2Apro and 3Cpro have been implicated in …

ABSTRACT The picornavirus Enterovirus D68 (EV-D68) is an important pathogen
associated with acute flaccid myelitis (AFM). The pathogenesis of AFM involves infection of …

Successful subversion of translation initiation factors 4E and 4G determines the infection
success of potyviruses, the largest group of viruses affecting plants. In the natural variability …

During apoptosis, caspases degrade 8 out of~ 30 nucleoporins to irreversibly demolish the
nuclear pore complex. However, for poorly understood reasons, caspases are also activated …

The nucleus is a hallmark organelle of eukaryotes. It separates the genetic material from the
rest of the cytoplasm using a selectively permeable double phospholipid bilayer called the …

The enterovirus genus comprises many human pathogens such as poliovirus,
coxsackievirus and rhinovirus. For efficient replication, enteroviruses induce membrane …