Neurotransmitters—key factors in neurological and neurodegenerative disorders of the central nervous system

RI Teleanu, AG Niculescu, E Roza… - International journal of …, 2022 - mdpi.com
Neurotransmitters are molecules that amplify, transmit, and convert signals in cells, having
an essential role in information transmission throughout the nervous system. Hundreds of …

Gut feelings: mechanosensing in the gastrointestinal tract

A Mercado-Perez, A Beyder - Nature Reviews Gastroenterology & …, 2022 - nature.com
The primary function of the gut is to procure nutrients. Synchronized mechanical activities
underlie nearly all its endeavours. Coordination of mechanical activities depends on …

Postoperative ileus and postoperative gastrointestinal tract dysfunction: pathogenic mechanisms and novel treatment strategies beyond colorectal enhanced recovery …

E Mazzotta, EC Villalobos-Hernandez… - Frontiers in …, 2020 - frontiersin.org
Postoperative ileus (POI) and postoperative gastrointestinal tract dysfunction (POGD) are
well-known complications affecting patients undergoing intestinal surgery. GI symptoms …

[HTML][HTML] Human-derived Bifidobacterium dentium modulates the mammalian serotonergic system and gut–brain axis

MA Engevik, B Luck, C Visuthranukul… - Cellular and molecular …, 2021 - Elsevier
Background & Aims The human gut microbiota can regulate production of serotonin (5-
hydroxytryptamine [5-HT]) from enterochromaffin cells. However, the mechanisms …

[HTML][HTML] RNA sensing by gut Piezo1 is essential for systemic serotonin synthesis

E Sugisawa, Y Takayama, N Takemura, T Kondo… - Cell, 2020 - cell.com
Gastrointestinal enterochromaffin cells regulate bone and gut homeostasis via serotonin (5-
hydroxytryptamine [5-HT]) production. A recent report suggested that gut microbes regulate …

Stretchable electrochemical sensors for cell and tissue detection

YL Liu, WH Huang - Angewandte Chemie International Edition, 2021 - Wiley Online Library
Electrochemical sensing based on conventional rigid electrodes has great restrictions for
characterizing biomolecules in deformed cells or soft tissues. The recent emergence of …

Understanding the effects of serotonin in the brain through its role in the gastrointestinal tract

JM Shine, C O'Callaghan, IC Walpola, G Wainstein… - Brain, 2022 - academic.oup.com
The neuromodulatory arousal system imbues the nervous system with the flexibility and
robustness required to facilitate adaptive behaviour. While there are well understood …

An insight into the roles of dietary tryptophan and its metabolites in intestinal inflammation and inflammatory bowel disease

X Li, ZH Zhang, HM Zabed, J Yun… - Molecular Nutrition & …, 2021 - Wiley Online Library
Inflammatory bowel disease (IBD) is complex, chronic, and relapsing gastrointestinal
inflammatory disorders, which includes mainly two conditions, namely ulcerative colitis (UC) …

Role of biomarker tests for diagnosis of neuroendocrine tumours

J Hofland, WT Zandee, WW de Herder - Nature Reviews Endocrinology, 2018 - nature.com
Neuroendocrine tumours (NETs) are neoplasms that arise from neuroendocrine cells.
Neuroendocrine cells and their tumours can secrete a wide range of amines and …

The tumor microenvironment in neuroendocrine tumors: biology and therapeutic implications

M Cives, E Pelle, D Quaresmini, FM Rizzo… - …, 2019 - karger.com
Neuroendocrine tumors (NETs) include a heterogeneous group of malignancies arising in
the diffuse neuroendocrine system and characterized by indolent growth. Complex …