Global burden, distribution and prevention of β-thalassemias and hemoglobin E disorders
R Colah, A Gorakshakar, A Nadkarni - Expert Review of …, 2010 - Taylor & Francis
The β-thalassemias, including the hemoglobin E disorders, are not only common in the
Mediterranean region, South-East Asia, the Indian subcontinent and the Middle East but …
Mediterranean region, South-East Asia, the Indian subcontinent and the Middle East but …
The significance of the hemoglobin A2 value in screening for hemoglobinopathies
BACKGROUND AND OBJECTIVE: The inherited hemoglobinopathies are a large group of
disorders that include thalassemias and hemoglobin variants. Accurate determination of the …
disorders that include thalassemias and hemoglobin variants. Accurate determination of the …
Significance of borderline HbA2 levels in β thalassemia carrier screening
Increased HbA2 levels are the characteristic feature of β-thalassemia carriers. A subset of
carriers however do not show HbA2 levels in the typical carrier range (≥ 4.0%) but show …
carriers however do not show HbA2 levels in the typical carrier range (≥ 4.0%) but show …
Borderline HbA2 levels: dilemma in diagnosis of beta-thalassemia carriers
There is inconsistency in the exact definition of diagnostic levels of HbA 2 for β thalassemia
trait. While many laboratories consider HbA 2≥ 4.0% diagnostic, still others consider HbA …
trait. While many laboratories consider HbA 2≥ 4.0% diagnostic, still others consider HbA …
Emerging point-of-care technologies for sickle cell disease diagnostics
S Ilyas, AE Simonson, W Asghar - Clinica Chimica Acta, 2020 - Elsevier
Sickle cell disease (SCD) is a serious and life-threatening disorder. SCD is considered a
public health issue affecting 25% of the population in Central and West Africa. Some …
public health issue affecting 25% of the population in Central and West Africa. Some …
HPLC in characterization of hemoglobin profile in thalassemia syndromes and hemoglobinopathies: a clinicohematological correlation
R Khera, T Singh, N Khuana, N Gupta… - Indian Journal of …, 2015 - Springer
High-performance liquid chromatography (HPLC) is a technique introduced for the accurate
diagnosis of hemoglobinopathies and thalassemias. The advantage of the HPLC system is …
diagnosis of hemoglobinopathies and thalassemias. The advantage of the HPLC system is …
Spectrum of haemoglobinopathies diagnosed by cation exchange-HPLC & modulating effects of nutritional deficiency anaemias from north India
Methods: A total of 800 blood samples were analyzed on the Bio-Rad Variant HPLC system
by β-thal short program. The retention times, proportion of the haemoglobin (%), and the …
by β-thal short program. The retention times, proportion of the haemoglobin (%), and the …
The genetics of blood disorders: hereditary hemoglobinopathies
Objective: To summarize recently published data on the pathophysiology, diagnosis and
treatment of sickle cell diseases and β-Thalassemias, the most relevant hereditary …
treatment of sickle cell diseases and β-Thalassemias, the most relevant hereditary …
Classification of complete blood count and haemoglobin ty** data by a C4. 5 decision tree, a naïve Bayes classifier and a multilayer perceptron for thalassaemia …
D Setsirichok, T Piroonratana, W Wongseree… - … Signal Processing and …, 2012 - Elsevier
This article presents the classification of blood characteristics by a C4. 5 decision tree, a
naïve Bayes classifier and a multilayer perceptron for thalassaemia screening. The aim is to …
naïve Bayes classifier and a multilayer perceptron for thalassaemia screening. The aim is to …
Unresolved laboratory issues of the heterozygous state of β-thalassemia: A literature review
S Thilakarathne, UP Jayaweera… - …, 2023 - pmc.ncbi.nlm.nih.gov
Although considered a mild clinical condition, many laboratory issues of the carrier state of β-
thalassemia remain unresolved. Accurate laboratory screening of β-thalassemia traits is …
thalassemia remain unresolved. Accurate laboratory screening of β-thalassemia traits is …