The burgeoning demand for novel cytotoxic drugs possessing improved bioavailability and
safety profiles has spurred the hybridization of various pharmacophores in the past decades …

The study focuses on green methodologies in synthetic organic chemistry, emphasizing the
use of thiamine hydrochloride (Vitamin B1) as an eco-friendly catalyst for synthesizing …

The development of new approaches for the synthesis of new bioactive heterocyclic
derivatives is of the utmost importance for pharmaceutical industry. In this regard, the …

Terephthalohydrazide chitosan hydrogel (TCs) was prepared and investigated as an
ecofriendly biopolymeric catalyst for synthesis of some novel thiazole and thiadiazole …

The catalytic activity of chitosan (Cs) and grafted Cs led to the preparation of
terephthalohydrazide Cs Schiff's base hydrogel (TCsSB), which was then investigated as an …

To highlight the importance of thiazole and thiadiazole derivatives in the progression of
cancer and microbial treatments and to aid in drug design, we have synthesized a new …

In this study, we investigated the in vitro antiproliferative activities and performed
computational studies of newly synthesized fluorinated isatin-hydrazones. The chemical …

Aim: This study focuses on advancing green chemistry in anticancer drug discovery,
particularly through the synthesis of azine derivatives with a naphthalene core using CS …

Green synthesis using L-proline as an organocatalyst is crucial due to its reusability, mild
conditions, clean reactions, easy workup, high purity, short reaction times, and high yields …

The escalating challenge of antibiotic resistance, responsible for nearly a fifth of global
fatalities, underscores the critical need for innovative therapeutic approaches and the …