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HMGB1 in the interplay between autophagy and apoptosis in cancer
Lysosome-mediated autophagy and caspase-dependent apoptosis are dynamic processes
that maintain cellular homeostasis, ensuring cell health and functionality. The intricate …
that maintain cellular homeostasis, ensuring cell health and functionality. The intricate …
Elucidating role of reactive oxygen species (ROS) in cisplatin chemotherapy: a focus on molecular pathways and possible therapeutic strategies
The failure of chemotherapy is a major challenge nowadays, and in order to ensure effective
treatment of cancer patients, it is of great importance to reveal the molecular pathways and …
treatment of cancer patients, it is of great importance to reveal the molecular pathways and …
[HTML][HTML] The interaction mechanism between autophagy and apoptosis in colon cancer
Q **e, Y Liu, X Li - Translational Oncology, 2020 - Elsevier
Autophagy and apoptosis play crucial roles in tumorigenesis. Recent studies have shown
that autophagy and apoptosis have a cross-talk relationship in anti-tumor therapy. It is well …
that autophagy and apoptosis have a cross-talk relationship in anti-tumor therapy. It is well …
Combination of an autophagy inducer and an autophagy inhibitor: a smarter strategy emerging in cancer therapy
T Liu, J Zhang, K Li, L Deng, H Wang - Frontiers in pharmacology, 2020 - frontiersin.org
Autophagy is considered a cytoprotective function in cancer therapy under certain conditions
and is a drug resistance mechanism that represents a clinical obstacle to successful cancer …
and is a drug resistance mechanism that represents a clinical obstacle to successful cancer …
[HTML][HTML] Blockage of autophagy for cancer therapy: a comprehensive review
The incidence and mortality of cancer are increasing, making it a leading cause of death
worldwide. Conventional treatments such as surgery, radiotherapy, and chemotherapy face …
worldwide. Conventional treatments such as surgery, radiotherapy, and chemotherapy face …
Voltage-gated potassium channels as regulators of cell death
Ion channels allow the flux of specific ions across biological membranes, thereby
determining ion homeostasis within the cells. Voltage-gated potassium-selective ion …
determining ion homeostasis within the cells. Voltage-gated potassium-selective ion …
Potassium channels: Novel targets for tumor diagnosis and chemoresistance
M Li, P Tian, Q Zhao, X Ma, Y Zhang - Frontiers in oncology, 2023 - frontiersin.org
In recent years, the role of potassium channels in tumors has been intensively studied.
Potassium channel proteins are widely involved in various physiological and pathological …
Potassium channel proteins are widely involved in various physiological and pathological …
[HTML][HTML] Potassium channels, tumorigenesis and targeted drugs
C **a, C Liu, S Ren, Y Cai, Q Zhang, C **a - Biomedicine & …, 2023 - Elsevier
Potassium channels play an important role in human physiological function. Recently,
various molecular mechanisms have implicated abnormal functioning of potassium …
various molecular mechanisms have implicated abnormal functioning of potassium …
The role of autophagy in gastric cancer chemoresistance: friend or foe?
JL Xu, L Yuan, YC Tang, ZY Xu, HD Xu… - Frontiers in Cell and …, 2020 - frontiersin.org
Gastric cancer is the third most common cause of cancer-related death worldwide. Drug
resistance is the main inevitable and vital factor leading to a low 5-year survival rate for …
resistance is the main inevitable and vital factor leading to a low 5-year survival rate for …
Challenges and therapeutic opportunities of autophagy in cancer therapy
VR Silva, SP Neves, LS Santos, RB Dias, DP Bezerra - Cancers, 2020 - mdpi.com
Simple Summary Autophagy is a physiological process characterized by the degradation of
the cell components through lysosomes due to stimuli/stress. In this study, we review the …
the cell components through lysosomes due to stimuli/stress. In this study, we review the …