Comparative genomics and molecular dynamics of DNA repeats in eukaryotes
Repeated elements can be widely abundant in eukaryotic genomes, composing more than
50% of the human genome, for example. It is possible to classify repeated sequences into …
50% of the human genome, for example. It is possible to classify repeated sequences into …
An update on precision genome editing by homology-directed repair in plants
J Chen, S Li, Y He, J Li, L **a - Plant Physiology, 2022 - academic.oup.com
Beneficial alleles derived from local landraces or related species, or even orthologs from
other plant species, are often caused by differences of one or several single-nucleotide …
other plant species, are often caused by differences of one or several single-nucleotide …
[HTML][HTML] High frequency retrotransposition in cultured mammalian cells
We previously isolated two human L1 elements (L1. 2 and LRE2) as the progenitors of
disease-producing insertions. Here, we show these elements can actively retrotranspose in …
disease-producing insertions. Here, we show these elements can actively retrotranspose in …
Human LINE retrotransposons generate processed pseudogenes
C Esnault, J Maestre, T Heidmann - Nature genetics, 2000 - nature.com
Long interspersed elements (LINEs) are endogenous mobile genetic elements 1, 2, 3, 4 that
have dispersed and accumulated in the genomes of higher eukaryotes via germline …
have dispersed and accumulated in the genomes of higher eukaryotes via germline …
Transcript-RNA-templated DNA recombination and repair
Homologous recombination is a molecular process that has multiple important roles in DNA
metabolism, both for DNA repair and genetic variation in all forms of life. Generally …
metabolism, both for DNA repair and genetic variation in all forms of life. Generally …
Genomic organization of plant terpene synthases and molecular evolutionary implications
SC Trapp, RB Croteau - Genetics, 2001 - academic.oup.com
Terpenoids are the largest, most diverse class of plant natural products and they play
numerous functional roles in primary metabolism and in ecological interactions. The first …
numerous functional roles in primary metabolism and in ecological interactions. The first …
Many human L1 elements are capable of retrotransposition
DM Sassaman, BA Dombroski, JV Moran… - Nature …, 1997 - nature.com
Using a selective screening strategy to enrich for active L1 elements, we isolated 13 full-
length elements from a human genomic library. We tested these and two previously-isolated …
length elements from a human genomic library. We tested these and two previously-isolated …
Precise gene replacement in rice by RNA transcript-templated homologous recombination
One of the main obstacles to gene replacement in plants is efficient delivery of a donor
repair template (DRT) into the nucleus for homology-directed DNA repair (HDR) of double …
repair template (DRT) into the nucleus for homology-directed DNA repair (HDR) of double …
Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death
GG Hicks, N Singh, A Nashabi, S Mai, G Bozek… - Nature …, 2000 - nature.com
The gene FUS (also known as TLS (for translocated in liposarcoma) and hnRNP P 2) is
translocated with the gene encoding the transcription factor ERG-1 in human myeloid …
translocated with the gene encoding the transcription factor ERG-1 in human myeloid …
Target site selection in transposition
NL Craig - Annual review of biochemistry, 1997 - annualreviews.org
Transposable elements are discrete mobile DNA segments that can insert into
nonhomologous target sites. Diverse patterns of target site selectivity are observed: Some …
nonhomologous target sites. Diverse patterns of target site selectivity are observed: Some …