Background Neurofibromatosis of types 1 and 2 (NF1, NF2) and schwannomatosis are the
diseases that make up the neurofibromatosis spectrum. With respective incidences of 1 in …

Meningiomas represent the most common primary brain tumor and comprise 3 World Health
Organization (WHO) grades, the most frequent being WHO grade I (90%). Surgery is …

Background NF2-related schwannomatosis (NF2-SWN, formerly called neurofibromatosis
type 2) is a tumor predisposition syndrome that is manifested by multiple vestibular …

Abstract Neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2), and
schwannomatosis (SWN) are tumor-suppressor syndromes. Each syndrome is an orphan …

Abstract Neurofibromatosis type 2 (NF2) is a genetic condition marked by the development
of multiple benign tumors in the nervous system. The most common tumors associated with …

Abstract Neurofibromatosis type 2 (NF2) is a tumor suppressor gene implicated in various
tumors, including mesothelioma, schwannomas, and meningioma. As a member of the ezrin …

Neurofibromatosis type 2 (NF2) is a rare autosomal dominant disorder (incidence 1: 33 000-
40 000) characterized by formation of central nervous system tumors, due to mutation in the …

Mutations in the neurofibromin 2 (NF2) gene were among the first genetic alterations
implicated in meningioma tumorigenesis, based on analysis of neurofibromatosis type 2 …

Objective: Neurofibromatosis (NF)-related benign tumors such as plexiform neurofibromas
(PN) and vestibular schwannomas (VS) can cause substantial morbidity. Clinical trials …

Abstract Neurofibromatosis type 2 (NF2) is a genetic disorder with bilateral vestibular
schwannomas (VS) as the most frequent manifestation. Merlin, the NF2 tumor suppressor …