[HTML][HTML] Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms
This work offers a general overview on the evolving strategies for the proteomic analysis of
snake venoms, and discusses how these may be combined through diverse experimental …
snake venoms, and discusses how these may be combined through diverse experimental …
Ending the drought: new strategies for improving the flow of affordable, effective antivenoms in Asia and Africa
The development of snake antivenoms more than a century ago should have heralded
effective treatment of the scourge of snakebite envenoming in impoverished, mostly rural …
effective treatment of the scourge of snakebite envenoming in impoverished, mostly rural …
Snake venom peptides: Tools of biodiscovery
Nature endowed snakes with a lethal secretion known as venom, which has been fine-tuned
over millions of years of evolution. Snakes utilize venom to subdue their prey and to survive …
over millions of years of evolution. Snakes utilize venom to subdue their prey and to survive …
Snake venomics: from the inventory of toxins to biology
JJ Calvete - Toxicon, 2013 - Elsevier
A deep understanding of the composition of venoms and of the principles governing the
evolution of venomous systems is of applied importance for exploring the enormous …
evolution of venomous systems is of applied importance for exploring the enormous …
Snake venom toxins: toxicity and medicinal applications
YS Chan, RCF Cheung, L **') to study the composition and natural history of snake venoms, and the cross …
Snake Venom PLA2, a Promising Target for Broad‐Spectrum Antivenom Drug Development
H **ao, H Pan, K Liao, M Yang… - BioMed research …, 2017 - Wiley Online Library
Snakebite envenomation is a neglected global health problem, causing substantial mortality,
disability, and psychological morbidity, especially in rural tropical and subtropical zones …
disability, and psychological morbidity, especially in rural tropical and subtropical zones …
Intraspecific venom variation in the medically significant Southern Pacific Rattlesnake (Crotalus oreganus helleri): biodiscovery, clinical and evolutionary implications
Due to the extreme variation of venom, which consequently results in drastically variable
degrees of neutralization by CroFab antivenom, the management and treatment of …
degrees of neutralization by CroFab antivenom, the management and treatment of …
Proteomics in evolutionary ecology: linking the genotype with the phenotype
AP Diz, M MARTÍNEZ‐FERNÁNDEZ… - Molecular …, 2012 - Wiley Online Library
The study of the proteome (proteomics), which includes the dynamics of protein expression,
regulation, interactions and its function, has played a less prominent role in evolutionary and …
regulation, interactions and its function, has played a less prominent role in evolutionary and …
New approaches & technologies of venomics to meet the challenge of human envenoming by snakebites in India
The direct estimate of 46,000 snakebite deaths in India in 2005 (1 for every 2 HIV/AIDS
deaths), based on verbal autopsies, renders unrealistic the total of only 47,000 snakebite …
deaths), based on verbal autopsies, renders unrealistic the total of only 47,000 snakebite …