Paralleling the increasing availability of protein-protein interaction (PPI) network data,
several network alignment methods have been proposed. Network alignments have been …

Hypusine modification of the eukaryotic initiation factor 5A (eIF-5A) is emerging as a crucial
regulator in cancer, infections, and inflammation. Although its contribution in translational …

The present study aimed to investigate the molecular mechanisms underlying glioblastoma
multiform (GBM) and its biomarkers. The differentially expressed genes (DEGs) were …

Network analysis has emerged as a powerful tool for examining structural biology systems.
The spatial organization of the components of a biomolecular structure has been rendered …

The evidence that two molecules interact in a living cell is often inferred from multiple
different experiments. Experimental data is captured in multiple repositories, but there is no …

Identification of protein complexes is fundamental for understanding the cellular functional
organization. With the accumulation of physical protein-protein interaction (PPI) data …

Many genes can play a role in multiple biological processes or molecular functions.
Identifying multifunctional genes at the genome-wide level and studying their properties can …

Intra-protein residue-level contact prediction has drawn a lot of attentions in recent years
and made very good progress, but much fewer methods are dedicated to inter-protein …

Background Clustering molecular network is a typical method in system biology, which is
effective in predicting protein complexes or functional modules. However, few studies have …

Since aberrant cell signaling pathways underlie majority of pathophysiological morbidities,
kinase inhibitors are routinely used for pharmacotherapy. However, most kinase inhibitors …