Traumatic spinal cord injury (SCI) has widespread physiological effects beyond the
disruption of sensory and motor function, notably the loss of normal autonomic and …

▪ Abstract Nerve regeneration is a complex biological phenomenon. In the peripheral
nervous system, nerves can regenerate on their own if injuries are small. Larger injuries …

Once their safety is confirmed, human-induced pluripotent stem cells (hiPSCs), which do not
entail ethical concerns, may become a preferred cell source for regenerative medicine …

▪ Abstract Nerve growth factor (NGF) was discovered 50 years ago as a molecule that
promoted the survival and differentiation of sensory and sympathetic neurons. Its roles in …

Murine and human iPSC-NS/PCs (induced pluripotent stem cell-derived neural
stem/progenitor cells) promote functional recovery following transplantation into the injured …

Neuropathic pain is a debilitating consequence of spinal cord injury (SCI) that remains
difficult to treat because underlying mechanisms are not yet fully understood. In part, this is …

Spinal cord injury (SCI) results not only in motor and sensory deficits but also in autonomic
dysfunctions. The disruption of connections between higher brain centers and the spinal …

Cardiovascular (CV) issues after spinal cord injury (SCI) are of paramount importance
considering they are the leading cause of death in this population. Disruption of autonomic …

Krassioukov A, Warburton DE, Teasell R, Eng JJ, Spinal Cord Injury Rehabilitation Evidence
Research Team. A systematic review of the management of autonomic dysreflexia after …

Stroke remains the leading cause of long-term disability with limited options available to aid
in recovery. Significant effort has been made to try and minimize neuronal damage following …