Cerebral small vessel disease: a review of the pathophysiological mechanisms

Y Hannawi - Translational Stroke Research, 2024 - Springer
Cerebral small vessel disease (cSVD) refers to the age-dependent pathological processes
involving the brain small vessels and leading to vascular cognitive impairment, intracerebral …

Effects of nutrition on cognitive function in adults with or without cognitive impairment: a systematic review of randomized controlled clinical trials

L Gutierrez, A Folch, M Rojas, JL Cantero, M Atienza… - Nutrients, 2021 - mdpi.com
New dietary approaches for the prevention of cognitive impairment are being investigated.
However, evidence from dietary interventions is mainly from food and nutrient supplement …

Dietary salt promotes neurovascular and cognitive dysfunction through a gut-initiated TH17 response

G Faraco, D Brea, L Garcia-Bonilla, G Wang… - Nature …, 2018 - nature.com
A diet rich in salt is linked to an increased risk of cerebrovascular diseases and dementia,
but it remains unclear how dietary salt harms the brain. We report that, in mice, excess …

Dietary salt promotes cognitive impairment through tau phosphorylation

G Faraco, K Hochrainer, SG Segarra, S Schaeffer… - Nature, 2019 - nature.com
Dietary habits and vascular risk factors promote both Alzheimer's disease and cognitive
impairment caused by vascular factors,–. Furthermore, accumulation of …

[HTML][HTML] Blood-brain barrier failure as a core mechanism in cerebral small vessel disease and dementia: evidence from a cohort study

JM Wardlaw, SJ Makin, MCV Hernández… - Alzheimer's & …, 2017 - Elsevier
Introduction Small vessel disease (SVD) is a common contributor to dementia. Subtle blood-
brain barrier (BBB) leakage may be important in SVD-induced brain damage. Methods We …

Hypertension, dietary salt and cognitive impairment

MM Santisteban, C Iadecola - Journal of Cerebral Blood …, 2018 - journals.sagepub.com
Dementia is growing at an alarming rate worldwide. Although Alzheimer disease is the
leading cause, over 50% of individuals diagnosed with Alzheimer disease have vascular …

Lifestyle and neurocognition in older adults with cognitive impairments: A randomized trial

JA Blumenthal, PJ Smith, S Mabe, A Hinderliter… - Neurology, 2019 - AAN Enterprises
Objective To determine the independent and additive effects of aerobic exercise (AE) and
the Dietary Approaches to Stop Hypertension (DASH) diet on executive functioning in adults …

Cerebral small vessel disease (CSVD)–lessons from the animal models

M Mustapha, CMNCM Nassir, N Aminuddin… - Frontiers in …, 2019 - frontiersin.org
Cerebral small vessel disease (CSVD) refers to a spectrum of clinical and imaging findings
resulting from pathological processes of various etiologies affecting cerebral arterioles …

STROKOG (stroke and cognition consortium): an international consortium to examine the epidemiology, diagnosis, and treatment of neurocognitive disorders in …

PS Sachdev, JW Lo, JD Crawford… - Alzheimer's & …, 2017 - Wiley Online Library
Abstract Introduction The Stroke and Cognition consortium (STROKOG) aims to facilitate a
better understanding of the determinants of vascular contributions to cognitive disorders and …

Reproducibility and variability of quantitative magnetic resonance imaging markers in cerebral small vessel disease

F De Guio, E Jouvent, GJ Biessels… - Journal of Cerebral …, 2016 - journals.sagepub.com
Brain imaging is essential for the diagnosis and characterization of cerebral small vessel
disease. Several magnetic resonance imaging markers have therefore emerged, providing …