Clonal fitness inferred from time-series modelling of single-cell cancer genomes

S Salehi, F Kabeer, N Ceglia, M Andronescu… - Nature, 2021 - nature.com
Progress in defining genomic fitness landscapes in cancer, especially those defined by copy
number alterations (CNAs), has been impeded by lack of time-series single-cell sampling of …

Statistical inference for stochastic differential equations

P Craigmile, R Herbei, G Liu… - Wiley Interdisciplinary …, 2023 - Wiley Online Library
Many scientific fields have experienced growth in the use of stochastic differential equations
(SDEs), also known as diffusion processes, to model scientific phenomena over time. SDEs …

Piecewise deterministic Markov processes for continuous-time Monte Carlo

P Fearnhead, J Bierkens, M Pollock, GO Roberts - Statistical Science, 2018 - JSTOR
Recently, there have been conceptually new developments in Monte Carlo methods through
the introduction of new MCMC and sequential Monte Carlo (SMC) algorithms which are …

Sequential quasi monte carlo

M Gerber, N Chopin - Journal of the Royal Statistical Society …, 2015 - academic.oup.com
We derive and study sequential quasi Monte Carlo (SQMC), a class of algorithms obtained
by introducing QMC point sets in particle filtering. SQMC is related to, and may be seen as …

Exact simulation of the Wright–Fisher diffusion

PA Jenkins, D Spano - 2017 - projecteuclid.org
Abstract The Wright–Fisher family of diffusion processes is a widely used class of
evolutionary models. However, simulation is difficult because there is no known closed-form …

Monte carlo fusion

H Dai, M Pollock, G Roberts - Journal of Applied Probability, 2019 - cambridge.org
In this paper we propose a new theory and methodology to tackle the problem of unifying
Monte Carlo samples from distributed densities into a single Monte Carlo draw from the …

Divide-and-Conquer Fusion

RSY Chan, M Pollock, AM Johansen… - arxiv preprint arxiv …, 2021 - arxiv.org
Combining several (sample approximations of) distributions, which we term sub-posteriors,
into a single distribution proportional to their product, is a common challenge. Occurring, for …

-Strong simulation for multidimensional stochastic differential equations via rough path analysis

J Blanchet, X Chen, J Dong - 2017 - projecteuclid.org
Consider a multidimensional diffusion process X={X(t):t∈0,1\}. Let ε>0 be a deterministic,
user defined, tolerance error parameter. Under standard regularity conditions on the drift …

On unbiased score estimation for partially observed diffusions

J Heng, J Houssineau, A Jasra - arxiv preprint arxiv:2105.04912, 2021 - arxiv.org
We consider the problem of statistical inference for a class of partially-observed diffusion
processes, with discretely-observed data and finite-dimensional parameters. We construct …

[PDF][PDF] The scalable Langevin exact algorithm: Bayesian inference for big data

M Pollock, P Fearnhead, AM Johansen… - arxiv preprint arxiv …, 2016 - researchgate.net
This paper introduces a class of Monte Carlo algorithms which are based upon simulating a
Markov process whose quasi-stationary distribution coincides with the distribution of interest …