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Endotheliopathy in acute COVID-19 and long COVID
The pulmonary endothelium is a highly regulated organ that performs a wide range of
functions under physiological and pathological conditions. Since endothelial dysfunction …
functions under physiological and pathological conditions. Since endothelial dysfunction …
Renin-angiotensin system and sex differences in COVID-19: a critical assessment
MC Chappell - Circulation Research, 2023 - ahajournals.org
The current epidemic of corona virus disease (COVID-19) has resulted in an immense
health burden that became the third leading cause of death and potentially contributed to a …
health burden that became the third leading cause of death and potentially contributed to a …
[HTML][HTML] Circulating ACE2 activity predicts mortality and disease severity in hospitalized COVID-19 patients
M Fagyas, Z Fejes, R Sütő, Z Nagy, B Székely… - International Journal of …, 2022 - Elsevier
Objectives Angiotensin-converting enzyme 2 (ACE2) represents the primary receptor for
SARS-CoV-2 to enter endothelial cells. Here we investigated circulating ACE2 activity to …
SARS-CoV-2 to enter endothelial cells. Here we investigated circulating ACE2 activity to …
Plasma ACE2 predicts outcome of COVID-19 in hospitalized patients
TW Kragstrup, HS Singh, I Grundberg, ALL Nielsen… - PloS one, 2021 - journals.plos.org
Aims Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to angiotensin
converting enzyme 2 (ACE2) enabling entrance of the virus into cells and causing the …
converting enzyme 2 (ACE2) enabling entrance of the virus into cells and causing the …
Low vitamin D levels predict outcomes of COVID-19 in patients with both severe and non-severe disease at hospitalization
Purpose Low vitamin D in COVID-19 have been related to worse outcomes. However, most
of the studies conducted so far were not-controlled and retrospective, including biases …
of the studies conducted so far were not-controlled and retrospective, including biases …
An ACE2 decoy can be administered by inhalation and potently targets omicron variants of SARS‐CoV‐2
L Zhang, KK Narayanan, L Cooper… - EMBO molecular …, 2022 - embopress.org
Monoclonal antibodies targeting the SARS‐CoV‐2 spike (S) neutralize infection and are
efficacious for the treatment of COVID‐19. However, SARS‐CoV‐2 variants, notably …
efficacious for the treatment of COVID‐19. However, SARS‐CoV‐2 variants, notably …
ACE2 Shedding and the Role in COVID-19
J Wang, H Zhao, Y An - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Angiotensin converting enzyme 2 (ACE2), a transmembrane glycoprotein, is an important
part of the renin-angiotensin system (RAS). In the COVID-19 epidemic, it was found to be the …
part of the renin-angiotensin system (RAS). In the COVID-19 epidemic, it was found to be the …
S protein, ACE2 and host cell proteases in SARS-CoV-2 cell entry and infectivity; is soluble ACE2 a two blade sword? A narrative review
R Nejat, MF Torshizi, DJ Najafi - Vaccines, 2023 - mdpi.com
Since the spread of the deadly virus SARS-CoV-2 in late 2019, researchers have restlessly
sought to unravel how the virus enters the host cells. Some proteins on each side of the …
sought to unravel how the virus enters the host cells. Some proteins on each side of the …
[HTML][HTML] Inflammatory biomarkers to predict the prognosis of acute bacterial and viral infections
Mortality in acute infections is mostly associated with sepsis, defined as 'life-threatening
organ dysfunction caused by a dysregulated host response to infection'. It remains …
organ dysfunction caused by a dysregulated host response to infection'. It remains …
Angiotensin-Converting Enzyme (ACE) level, but not ACE gene polymorphism, is associated with prognosis of COVID-19 infection: Implications for diabetes and …
O Elbasan, F Bayram, CD Yazan, T Apaydın… - PloS one, 2023 - journals.plos.org
Background The renin-angiotensin-aldosterone system was shown to be activated in severe
COVID-19 infection. We aimed to investigate the relationship between angiotensin …
COVID-19 infection. We aimed to investigate the relationship between angiotensin …