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Pathogenic mechanisms following ischemic stroke
Stroke is the second most common cause of death and the leading cause of disability
worldwide. Brain injury following stroke results from a complex series of pathophysiological …
worldwide. Brain injury following stroke results from a complex series of pathophysiological …
Ischemia-reperfusion injury in the brain: mechanisms and potential therapeutic strategies
L Lin, X Wang, Z Yu - Biochemistry & pharmacology: open …, 2016 - pmc.ncbi.nlm.nih.gov
Ischemia-reperfusion injury is a common feature of ischemic stroke, which occurs when
blood supply is restored after a period of ischemia. Reperfusion can be achieved either by …
blood supply is restored after a period of ischemia. Reperfusion can be achieved either by …
Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use
Neuroprotection and brain repair in patients after acute brain damage are still major
unfulfilled medical needs. Pharmacological treatments are either ineffective or confounded …
unfulfilled medical needs. Pharmacological treatments are either ineffective or confounded …
Postconditioning and protection from reperfusion injury: where do we stand? Position paper from the Working Group of Cellular Biology of the Heart of the European …
Ischaemic postconditioning (brief periods of ischaemia alternating with brief periods of
reflow applied at the onset of reperfusion following sustained ischaemia) effectively reduces …
reflow applied at the onset of reperfusion following sustained ischaemia) effectively reduces …
Methods, devices, and systems for postconditioning with clot removal
A Turjman, J Bernstein - US Patent 9,445,828, 2016 - Google Patents
(57) New devices, systems, and methods are disclosed for pre venting, treating, and/or at
least minimizing ischemia and/or reperfusion injury by restoring and/or modulating blood …
least minimizing ischemia and/or reperfusion injury by restoring and/or modulating blood …
Neuroprotective effect of Danhong injection on cerebral ischemia-reperfusion injury in rats by activation of the PI3K-Akt pathway
C Feng, H Wan, Y Zhang, L Yu, C Shao, Y He… - Frontiers in …, 2020 - frontiersin.org
Many traditional Chinese medicines, including Danhong injection (DHI), can be used to treat
cerebral ischemia-reperfusion injury and have neuroprotective effects on the brain; however …
cerebral ischemia-reperfusion injury and have neuroprotective effects on the brain; however …
Limb remote ischemic postconditioning protects against focal ischemia in rats
Remote ischemic postconditioning (RIP) refers to an ischemia conducted in a distant organ
that protects against a prior ischemia in another organ. We tested whether RIP protects …
that protects against a prior ischemia in another organ. We tested whether RIP protects …
Sirtuin 6 protects the brain from cerebral ischemia/reperfusion injury through NRF2 activation
W Zhang, R Wei, L Zhang, Y Tan, C Qian - Neuroscience, 2017 - Elsevier
Abstract Sirtuin 6 (SIRT6), a member of the sirtuin family of NAD (+)-dependent
deacetylases, has been shown to produce beneficial effects in myocardial …
deacetylases, has been shown to produce beneficial effects in myocardial …
Ischemic postconditioning as a novel avenue to protect against brain injury after stroke
H Zhao - Journal of Cerebral Blood Flow & Metabolism, 2009 - journals.sagepub.com
Ischemic postconditioning initially referred to a stuttering reperfusion performed immediately
after reperfusion, for preventing ischemia/reperfusion injury in both myocardial and cerebral …
after reperfusion, for preventing ischemia/reperfusion injury in both myocardial and cerebral …
Pharmacological postconditioning: a molecular aspect in ischemic injury
Abstract Objective Ischaemia/reperfusion (I/R) injury is defined as the damage to the tissue
which is caused when blood supply returns to tissue after ischaemia. To protect the …
which is caused when blood supply returns to tissue after ischaemia. To protect the …