A treat-to-target (T2T) approach applies the principles of early intervention and tight disease
control to optimise long-term outcomes in Crohn's disease. The Selecting Therapeutic …

Though distinct in terms of pathology, natural history and therapeutic approach, irritable
bowel syndrome (IBS) and inflammatory bowel disease (IBD) have some features in …

Chronic diarrhoea is a common problem, hence clear guidance on investigations is
required. This is an updated guideline from 2003 for the investigations of chronic diarrhoea …

Parkinson's disease (PD) is characterized by alpha-synuclein misfolding with subsequent
intraneuronal amyloid formation and accumulation, low grade neuroinflammatory changes …

Objectives: The aim of the study was to review the evidence regarding the clinical use and
value of fecal calprotectin (FC) measurements in different gastrointestinal disorders in …

Abstract Background and Aims Preliminary evidence suggests that fermentable
carbohydrate restriction might ameliorate functional gastrointestinal symptoms [FGS] in …

Background The diagnosis of colorectal cancer (CRC) can be difficult as symptoms are
variable with poor specificity. Thus, there is a quest for simple, non‐invasive testing that can …

Background & Aims Mucosal healing is associated with improved outcomes in patients with
Crohn's disease (CD), but assessment typically requires ileocolonoscopy. Calprotectin can …

Background Micro‐inflammation is considered an element in the pathogenesis of irritable
bowel syndrome (IBS). High‐sensitivity C reactive protein (hs‐CRP) was previously shown …

Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease
(CD), is a costly condition in terms of morbidity and healthcare utilization, with an increasing …