Positron Emission Tomography (PET) experienced accelerated development and has
become an established method for medical research and clinical routine diagnostics on …

This article reviews the development of bifunctional chelates for synthesising 68 Ga
radiopharmaceuticals. It structures the chelates into groups of macrocycles …

In recent years, Positron Emission Tomography (PET) has become a practical, high
performance clinical imaging modality for visualization of biological process within the living …

The diagnosis of bacterial infections at deep body sites benefits from noninvasive imaging of
molecular probes that can be traced by positron emission tomography (PET). We specifically …

Gallium-68 is rapidly gaining importance, as this generator-produced PET isotope is
available independent of on-site cyclotrons, enabling radiopharmaceutical production with …

Background In the context of nuclear medicine and theranostics, integrin-related research
and development was, for most of the time, focused predominantly on'RGD peptides' and the …

Expression of the cellular transmembrane receptor αvβ6 integrin is essentially restricted to
malignant epithelial cells in carcinomas of a broad variety of lineages, whereas it is virtually …

Targeted therapy has become an effective strategy of precision medicine for cancer
treatment. Based on the success of antibody-drug conjugates (ADCs), here we report a …

INTRODUCTION: The rekindled interest in the 68Ga generator as an attractive positron
emission tomography generator system has led us and others to investigate novel chelate …

Carbonic anhydrase IX (CA-IX) is a HIF-1-inducible enzyme that is overexpressed in many
cancer subtypes to promote survival and invasion in hypoxic niches. Pharmacologic …