Charged particle therapy has been largely driven and influenced by nuclear physics. The
increase in energy deposition density along the ion path in the body allows reducing the …

The main advantages of proton therapy are the reduced total energy deposited in the patient
as compared to photon techniques and the finite range of the proton beam. The latter adds …

Protons are an interesting modality for radiotherapy because of their well defined range and
favourable depth dose characteristics. On the other hand, these same characteristics lead to …

Purpose: TOPAS (TOol for PArticle Simulation) is a particle simulation code recently
developed with the specific aim of making Monte Carlo simulations user‐friendly for …

We present a comprehensive analytical comparison of four types of proton imaging set-ups
and, to this end, develop a mathematical framework to calculate the width of the uncertainty …

We present a proof of principle study of proton radiography and proton computed
tomography (pCT) based on time-resolved dose measurements. We used a prototype, two …

In vivo PET range verification relies on the comparison of measured and simulated activity
distributions. The accuracy of the simulated distribution depends on the accuracy of the …

Online proton range/dose verification based on measurements of proton-induced positron
emitters is a promising strategy for quality assurance in proton therapy. Because of the …

Purpose In vivo range verification in proton therapy is a critical step to help minimize range
and dose uncertainty. We propose to employ a time reversal (TR)‐based approach using …

Proton therapy can be particularly sensitive to changes or errors in range. Thus, methods for
the in vivo measurement of range could be of great use to improve the quality and accuracy …