Cognitive impairment and neurodegenerative diseases development associated with organophosphate pesticides exposure: a review study
M Sarailoo, S Afshari, V Asghariazar… - Neurotoxicity …, 2022 - Springer
A significant body of literature emphasizes the role of insecticide, particularly
organophosphates (OPs), as the major environmental factor in the etiology of …
organophosphates (OPs), as the major environmental factor in the etiology of …
Beyond the behavioural phenotype: Uncovering mechanistic foundations in aquatic eco-neurotoxicology
During the last decade, there has been an increase in awareness of how anthropogenic
pollution can alter behavioural traits of diverse aquatic organisms. Apart from understanding …
pollution can alter behavioural traits of diverse aquatic organisms. Apart from understanding …
Neuropsychiatric disorders in farmers associated with organophosphorus pesticide exposure in a rural village of Northwest México
A Serrano-Medina, A Ugalde-Lizárraga… - International journal of …, 2019 - mdpi.com
This study aims to determine the degree of acetylcholinesterase inhibition and neurological
symptoms for each of the psychiatric disorders diagnosed in the farm workers of a rural …
symptoms for each of the psychiatric disorders diagnosed in the farm workers of a rural …
Dugesia japonica is the best suited of three planarian species for high-throughput toxicology screening
D Ireland, V Bochenek, D Chaiken, C Rabeler, S Onoe… - Chemosphere, 2020 - Elsevier
High-throughput screening (HTS) using new approach methods is revolutionizing
toxicology. Asexual freshwater planarians are a promising invertebrate model for …
toxicology. Asexual freshwater planarians are a promising invertebrate model for …
[HTML][HTML] PBDEs disrupt homeostasis maintenance and regeneration of planarians due to DNA damage, proliferation and apoptosis anomaly
Y Yang, L Wang, Y Zhao, F Ma, Z Lin, Y Liu… - Ecotoxicology and …, 2022 - Elsevier
Polybrominated diphenyl ethers (PBDEs) are widely used as brominated flame retardants in
the manufacturing industry, belonging to persistent organic pollutants in the environment …
the manufacturing industry, belonging to persistent organic pollutants in the environment …
Differences in neurotoxic outcomes of organophosphorus pesticides revealed via multi-dimensional screening in adult and regenerating planarians
Organophosphorus pesticides (OPs) are a chemically diverse class of commonly used
insecticides. Epidemiological studies suggest that low dose chronic prenatal and infant …
insecticides. Epidemiological studies suggest that low dose chronic prenatal and infant …
Bioactivation and detoxification of organophosphorus pesticides in freshwater planarians shares similarities with humans
D Ireland, C Rabeler, TX Gong, EMS Collins - Archives of toxicology, 2022 - Springer
Organophosphorus pesticides (OPs) are a chemically diverse class of insecticides that
inhibit acetylcholinesterase (AChE). Many OPs require bioactivation to their active oxon form …
inhibit acetylcholinesterase (AChE). Many OPs require bioactivation to their active oxon form …
Toxicity of herbicide glyphosate to planarian Dugesia japonica and its potential molecular mechanisms
HC Zhang, CY Shi, WJ Zhao, GW Chen, DZ Liu - Aquatic Toxicology, 2023 - Elsevier
Glyphosate (GLY) is one of the most widely used agrochemicals in the world, and its
exposure has become a public health concern. The freshwater planarian is an ideal test …
exposure has become a public health concern. The freshwater planarian is an ideal test …
Screening for neurotoxic potential of 15 flame retardants using freshwater planarians
S Zhang, D Ireland, NS Sipes, M Behl… - Neurotoxicology and …, 2019 - Elsevier
Asexual freshwater planarians are an attractive invertebrate model for high-throughput
neurotoxicity screening, because they possess multiple quantifiable behaviors to assess …
neurotoxicity screening, because they possess multiple quantifiable behaviors to assess …
New worm on the block: Planarians in (neuro) toxicology
D Ireland, EMS Collins - Current protocols, 2022 - Wiley Online Library
Traditional mammalian testing is too time‐and cost‐intensive to keep up with the large
number of environmental chemicals needing assessment. This has led to a dearth of …
number of environmental chemicals needing assessment. This has led to a dearth of …