Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …

Current disease resistance breeding, which is largely dependent on the exploitation of
resistance genes in host plants, faces the serious challenges of rapidly evolving …

Liquid chromatography-mass spectrometry (LC-MS) based untargeted metabolomics allows
to measure both known and unknown metabolites in the metabolome. However, unknown …

Abstract microbeMASST, a taxonomically informed mass spectrometry (MS) search tool,
tackles limited microbial metabolite annotation in untargeted metabolomics experiments …

Plants have been an essential source of human medicine for millennia. In this review, we
argue that a holistic, interdisciplinary approach to the study of medicinal plants that …

Studies of the human microbiome share both technical and conceptual similarities with
genome-wide association studies and genetic epidemiology. However, the microbiome has …

Background Icariin (ICA), an active ingredient extracted from Epimedium species, has
shown promising results in the treatment of Alzheimer's disease (AD), although its potential …

Microbiomes occupy a range of niches and, in addition to having diverse compositions, they
have varied functional roles that have an impact on agriculture, environmental sciences, and …

Natural ecosystems harbor a huge reservoir of taxonomically diverse microbes that are
important for plant growth and health. The vast diversity of soil microorganisms and their …

Humus formation of composting is crucial for improving organic fertilizer quality. Biochar has
been found to be a low-cost, eco-friendly and effective promoter for humus formation, while …