The endocannabinoid (eCB) system is one the most ubiquitous signaling systems of the
brain and offers a rich pharmacology including multiple druggable targets. Preclinical …

Posttraumatic stress disorder (PTSD) is associated with heightened emotional responding,
avoidance of trauma related stimuli, and physical health concerns (eg, metabolic syndrome …

Post-traumatic stress disorder (PTSD) is a common, debilitating condition with limited
treatment options. Extinction of fear memories through prolonged exposure therapy, the …

Background and Purpose Women are twice as likely as men to develop post‐traumatic
stress disorder (PTSD) making the search for biological mechanisms underlying these …

The therapeutic benefits of the current medications for patients with psychiatric disorders
contrast with a great variety of adverse effects. The endocannabinoid system (ECS) …

Cannabis is well established to impact affective states, emotion and perceptual processing,
primarily through its interactions with the endocannabinoid system. While cannabis use is …

Memory formation enables the retention of life experiences overtime. Based on previously
acquired information, organisms can anticipate future events and adjust their behaviors to …

Introduction We recently demonstrated that moderate-intensity aerobic exercise delivered
during the consolidation of fear extinction learning reduced threat expectancy during a test …

Endocannabinoids were implicated in a variety of pathological conditions including anxiety
and are considered promising new targets for anxiolytic drug development. The optimism …

Increased anandamide (AEA) signaling through inhibition of its catabolic enzyme fatty acid
amide hydrolase (FAAH) in the basolateral complex of amygdala (BLA) is thought to buffer …