Metabolic syndrome is a type of multifactorial metabolic disease with the presence of at least
three factors: obesity, diabetes mellitus, low high-density lipoprotein, hypertriglyceridemia …

Cholesterol plays important roles in many physiological processes, including cell membrane
structure and function, hormone synthesis, and the regulation of cellular homeostasis. The …

Triple-negative breast cancer (TNBC) is more prone to recurrence and metastasis relative to
other subtypes of breast cancer, leading to an extremely poor prognosis. The increasing …

Purpose The objectives of this work were to investigate whether the serum-free fatty acid
(FFA) level is meaningful in cancer patients and its role in cancer diagnosis. Methods A total …

Introduction Statins, HMG-CoA reductase inhibitors, are commonly used cholesterol-
lowering medications which are also increasingly recognized to have anti-cancer properties …

Purpose Statins are the most widely prescribed cholesterol lowering medications and have
been associated with both improved and unchanged breast cancer outcomes in previous …

Simple Summary For tumors to initiate and sustain rapid growth, they need to alter their
metabolic reprograming to support this growth. While many oncogenes upregulate …

Background: Statin, a lipid-lowering drug, has been suggested to confer anticancer efficacy.
However, previous studies evaluating the association between statin use and prognosis in …

Pre-clinical studies in triple negative breast cancer (TNBC) suggest that statins may inhibit
cell proliferation, promote cell-cycle arrest, induce apoptosis, change the tumor …

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