Structure, assembly, and function of tripartite efflux and type 1 secretion systems in gram-negative bacteria

I Alav, J Kobylka, MS Kuth, KM Pos, M Picard… - Chemical …, 2021 - ACS Publications
Tripartite efflux pumps and the related type 1 secretion systems (T1SSs) in Gram-negative
organisms are diverse in function, energization, and structural organization. They form …

Tandem repeats lead to sequence assembly errors and impose multi-level challenges for genome and protein databases

OK Tørresen, B Star, P Mier… - Nucleic acids …, 2019 - academic.oup.com
The widespread occurrence of repetitive stretches of DNA in genomes of organisms across
the tree of life imposes fundamental challenges for sequencing, genome assembly, and …

Structural insight reveals SARS-CoV-2 ORF7a as an immunomodulating factor for human CD14+ monocytes

Z Zhou, C Huang, Z Zhou, Z Huang, L Su, S Kang… - IScience, 2021 - cell.com
Dysregulated immune cell responses have been linked to the severity of coronavirus
disease 2019 (COVID-19), but the specific viral factors of severe acute respiratory syndrome …

Polymer self-assembly induced enhancement of ice recrystallization inhibition

PG Georgiou, HL Marton, AN Baker… - Journal of the …, 2021 - ACS Publications
Ice binding proteins modulate ice nucleation/growth and have huge (bio) technological
potential. There are few synthetic materials that reproduce their function, and rational design …

Microfluidic-Based Oxygen (O2) Sensors for On-Chip Monitoring of Cell, Tissue and Organ Metabolism

M Azimzadeh, P Khashayar, M Amereh, N Tasnim… - Biosensors, 2021 - mdpi.com
Oxygen (O2) quantification is essential for assessing cell metabolism, and its consumption in
cell culture is an important indicator of cell viability. Recent advances in microfluidics have …

From input to output: the Lap/c-di-GMP biofilm regulatory circuit

AJ Collins, TJ Smith, H Sondermann… - Annual review of …, 2020 - annualreviews.org
Biofilms are the dominant bacterial lifestyle. The regulation of the formation and dispersal of
bacterial biofilms has been the subject of study in many organisms. Over the last two …

High molecular weight polyproline as a potential biosourced ice growth inhibitor: synthesis, ice recrystallization inhibition, and specific ice face binding

N Judge, PG Georgiou, A Bissoyi, A Ahmad… - …, 2023 - ACS Publications
Ice-binding proteins (IBPs) from extremophile organisms can modulate ice formation and
growth. There are many (bio) technological applications of IBPs, from cryopreservation to …

The Pseudomonas aeruginosa biofilm matrix protein CdrA has similarities to other fibrillar adhesin proteins

C Reichhardt - Journal of bacteriology, 2023 - Am Soc Microbiol
The ability of bacteria to adhere to each other and both biotic and abiotic surfaces is key to
biofilm formation, and one way that bacteria adhere is using fibrillar adhesins. Fibrillar …

A peptide-binding domain shared with an Antarctic bacterium facilitates Vibrio cholerae human cell binding and intestinal colonization

CJ Lloyd, S Guo, B Kinrade, H Zahiri… - Proceedings of the …, 2023 - National Acad Sciences
Vibrio cholerae, the causative agent of the disease cholera, is responsible for multiple
pandemics. V. cholerae binds to and colonizes the gastrointestinal tract within the human …

Ice recrystallization inhibition activity varies with ice-binding protein type and does not correlate with thermal hysteresis

AK Gruneberg, LA Graham, R Eves, P Agrawal… - Cryobiology, 2021 - Elsevier
Ice-binding proteins (IBPs) inhibit the growth of ice through surface adsorption. In some
freeze-resistant fishes and insects, circulating IBPs serve as antifreeze proteins to stop ice …