The prevalence of obesity has reached pandemic proportions, and now approximately 25%
of adults in Westernized countries have obesity. Recognized as a major health concern …

Objective To perform a large-scale pairwise and network meta-analysis on the effects of all
relevant exercise training modes on resting blood pressure to establish optimal …

There is a pandemic of physical inactivity that appears to parallel the widespread
prevalence of cardiovascular disease (CVD). Yet, regular physical activity (PA) and exercise …

The burden of chronic kidney disease (CKD) and its risk factors are projected to rise in
parallel with the rapidly ageing global population. By 2050, the prevalence of CKD category …

Background: Although lifestyle modifications generally are effective in lowering blood
pressure (BP) among patients with unmedicated hypertension and in those treated with 1 or …

Background Although exercise training reduces office blood pressure (BP), scarcer
evidence is available on whether these benefits also apply to ambulatory blood pressure …

Today's challenge for precision medicine involves the integration of the impact of molecular
clocks on drug pharmacokinetics, toxicity, and efficacy toward personalized chronotherapy …

Background Cardiometabolic multimorbidity (CMM) is becoming increasingly common in
patients with hypertension, and it is well established that healthy lifestyle plays a key role in …

Background High-intensity interval training (HIIT) remains a promising exercise mode in
managing cardiometabolic health. Large-scale analyses are necessary to understand its …

We aimed to evaluate the dose-dependent effects of aerobic exercise on systolic (SBP) and
diastolic blood pressure (DBP) and haemodynamic factors in adults with hypertension …