Current developments of coumarin-based anti-cancer agents in medicinal chemistry
S Emami, S Dadashpour - European Journal of Medicinal Chemistry, 2015 - Elsevier
Cancer is one of the leading health hazards and the prominent cause of death in the world.
A number of anticancer agents are currently in clinical practice and used for treatment of …
A number of anticancer agents are currently in clinical practice and used for treatment of …
A comprehensive review in current developments of benzothiazole-based molecules in medicinal chemistry
Benzothiazole (BTA) and its derivatives are the most important heterocyclic compounds,
which are common and integral feature of a variety of natural products and pharmaceutical …
which are common and integral feature of a variety of natural products and pharmaceutical …
Magnetically recoverable catalysts: Catalysis in synthesis of polyhydroquinolines
M Kazemi, M Mohammadi - Applied Organometallic Chemistry, 2020 - Wiley Online Library
Molecules that contain polyhydroquinoline structural scaffolds are N‐containing
heterocycles which are of great interest to organic chemists and biologists …
heterocycles which are of great interest to organic chemists and biologists …
Current developments of coumarin compounds in medicinal chemistry
XM Peng, G LV Damu, C He Zhou - Current pharmaceutical …, 2013 - benthamdirect.com
Coumarin compounds represent an important type of naturally occurring and synthetic
oxygen-containing heterocycles with typical benzopyrone framework. This type of special …
oxygen-containing heterocycles with typical benzopyrone framework. This type of special …
Recent advances in the synthesis of 2-substituted benzothiazoles: a review
Benzothiazole can serve as unique and versatile scaffolds, especially in synthetic and
pharmaceutical chemistry because of their potent and significant pharmacological activities …
pharmaceutical chemistry because of their potent and significant pharmacological activities …
New thiazol-hydrazono-coumarin hybrids targeting human cervical cancer cells: Synthesis, CDK2 inhibition, QSAR and molecular docking studies
Motivated by the potential anticancer activity of both coumarin and 2-aminothiazole nuclei, a
new set of thiazol-2-yl hydrazono-chromen-2-one analogs were efficiently synthesized …
new set of thiazol-2-yl hydrazono-chromen-2-one analogs were efficiently synthesized …
Synthesis and biological evaluation of novel tacrine derivatives and tacrine–coumarin hybrids as cholinesterase inhibitors
S Hamulakova, L Janovec, M Hrabinova… - Journal of medicinal …, 2014 - ACS Publications
A series of novel tacrine derivatives and tacrine–coumarin heterodimers were designed,
synthesized, and biologically evaluated for their potential inhibitory effect on both …
synthesized, and biologically evaluated for their potential inhibitory effect on both …
Novel coumarin derivatives bearing N-benzyl pyridinium moiety: potent and dual binding site acetylcholinesterase inhibitors
A novel series of coumarin derivatives linked to benzyl pyridinium group were synthesized
and biologically evaluated as inhibitors of both acetylcholinesterase (AChE) and …
and biologically evaluated as inhibitors of both acetylcholinesterase (AChE) and …
Synthesis of a novel chloroquinoline, rhodanine encompassed 1, 2, 3-triazole scaffolds and molecular docking evaluation of their cytotoxicity
A novel series of quinoline-linked rhodanine bearing 1, 2, 3-triazole analogs (10a-l) have
been designed and prepared. All the novel hybrids were analyzed and characterized by …
been designed and prepared. All the novel hybrids were analyzed and characterized by …
Excellent antitumor and antimetastatic activities based on novel coumarin/pyrazole oxime hybrids
H Dai, M Huang, J Qian, J Liu, C Meng, Y Li… - European journal of …, 2019 - Elsevier
A series of hybrids 10a-v based on coumarin/pyrazole oxime have been synthesized, and
exhibit good to excellent antitumor activities. Compound 10n has shown remarkable …
exhibit good to excellent antitumor activities. Compound 10n has shown remarkable …