N-Heterocyclic carbenes (NHCs) have become without doubt one of the most exciting and
popular species in chemical science due to the ease of their preparation and modularity in …

Cyclic (alkyl)-and (aryl)-(amino) carbenes (CAACs and CAArCs) are stronger σ-donors and
π-acceptors than imidazol-2-ylidenes and imidazolidin-2-ylidenes, the well-known N …

The clinical success of platinum-based chemotherapeutic agents was of enormous impact
on the discovery of novel metal N-heterocyclic carbene (NHC) complexes as potential anti …

The discovery of cisplatin's antitumor activity in 1969 prompted the search for novel metal-
containing complexes as potential anticancer drugs. Among these novel complexes, metal N …

Metal complexes with N-heterocyclic carbene (NHC) ligands are widely used in chemistry
due to their catalytic properties and applied for olefin metathesis among other reactions. The …

A new era of metal-based drugs started in the 1960s, heralded by the discovery of potent
platinum-based complexes, commencing with cisplatin [(H3N) 2PtCl2], which are effective …

From wedding rings on fingers to stained glass windows, by way of Olympic medals, gold
has been highly prized for millennia. Nowadays, organometallic gold compounds occupy an …

The Organometallic Chemistry of N-heterocyclic Carbenes describes various aspects of N-
heterocyclic Carbenes (NHCs) and their transition metal complexes at an entry level suitable …

Within the research field of antitumor metal-based agents alternative to platinum drugs, gold
(I/III) coordination complexes have always been in the forefront due mainly to the familiarity …

Cancer, also known as malignant neoplasm, is a dreadful disease which involves abnormal
cell growth having the potential to invade or spread to other parts of the body …