Oxygen-derived free radicals and related oxidants are ubiquitous and short-lived
intermediates formed in aerobic organisms throughout life. These reactive species …

Peroxynitrite is a short-lived and reactive biological oxidant formed from the diffusion-
controlled reaction of the free radicals superoxide (O2•–) and nitric oxide (• NO). In this …

Melatonin is an ancient antioxidant. After its initial development in bacteria, it has been
retained throughout evolution such that it may be or may have been present in every species …

In this review we provide an analysis of the biochemistry of peroxynitrite and tyrosine
nitration. Peroxynitrite is the product of the diffusion-controlled reaction between superoxide …

Peroxynitrite is the product of the diffusion-controlled reaction of nitric oxide and superoxide
radicals. Peroxynitrite, a reactive short-lived peroxide with ap K a of 6.8, is a good oxidant …

Conspectus In an aerobic organism, reactive oxygen species (ROS) are an inevitable
metabolic byproduct. Endogenously produced ROS have a significant role in physiological …

This review article presents a comprehensive review pertaining to antioxidants and various
assays that determined enzymatic and nonenzymatic antioxidants. Antioxidants have gained …

The mechanistic properties of two dietary antioxidants that are required by humans, vitamins
C and E, are discussed relative to their biological effects. Vitamin C (ascorbic acid) is an …

The present manuscript is a conceptual review concerning the photo-Fenton reaction at near-
neutral pH, used for bacterial inactivation. In this first Part, an overview of the mechanisms …

Peroxynitrite (OONO–) is profoundly implicated in health and disease. The physiological and
pathological outcome of OONO–is related to its local concentration, and hence, a reliable …