MicroRNAs (miRNAs) are small noncoding RNAs that typically inhibit the translation and
stability of messenger RNAs (mRNAs), controlling genes involved in cellular processes such …

Tumors are cellularly and molecularly heterogeneous, with subsets of undifferentiated
cancer cells exhibiting stem cell-like features (CSCs). Epithelial to mesenchymal transitions …

Background RNA-seq is widely used for transcriptomic profiling, but the bioinformatics
analysis of resultant data can be time-consuming and challenging, especially for biologists …

Over the past several years it has become clear that alterations in the expression of
microRNA (miRNA) genes contribute to the pathogenesis of most—if not all—human …

One of the main engines that drives cellular transformation is the loss of proper control of the
mammalian cell cycle. The cyclin-dependent kinase inhibitor p21 (also known as …

The canonical role of messenger RNA (mRNA) is to deliver protein-coding information to
sites of protein synthesis. However, given that microRNAs bind to RNAs, we hypothesized …

MicroRNAs are small, highly conserved non-coding RNA molecules involved in the
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …

Gastric cancer (GC) is one of the most common tumors worldwide and the leading cause of
tumor-related mortality. Endoscopy and serological tumor marker testing are currently the …

MicroRNAs (miRNAs) are small, noncoding RNAs with important functions in development,
cell differentiation, and regulation of cell cycle and apoptosis. MiRNA expression is …

MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs that regulate
gene expression. Early studies have shown that miRNA expression is deregulated in cancer …