Review on Alzheimer's disease: inhibition of amyloid beta and tau tangle formation

H Ashrafian, EH Zadeh, RH Khan - International journal of biological …, 2021 - Elsevier
It is reported that approximately 40 million people are suffering from dementia, globally.
Dementia is a group of symptoms that affect neurons and cause some mental disorders …

Protein aggregation: from background to inhibition strategies

P Alam, K Siddiqi, SK Chturvedi, RH Khan - International journal of …, 2017 - Elsevier
The aggregation of specific proteins is hypothesized to cause several pathological
conditions, which are collectively known as amyloid disorders. The aggregation of peptides …

Vitamin k3 inhibits protein aggregation: implication in the treatment of amyloid diseases

P Alam, SK Chaturvedi, MK Siddiqi, RK Rajpoot… - Scientific reports, 2016 - nature.com
Protein misfolding and aggregation have been associated with several human diseases
such as Alzheimer's, Parkinson's and familial amyloid polyneuropathy etc. In this study, anti …

Journey on naphthoquinone and anthraquinone derivatives: new insights in Alzheimer's disease

M Campora, V Francesconi, S Schenone, B Tasso… - Pharmaceuticals, 2021 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease that is characterized
by memory loss, cognitive impairment, and functional decline leading to dementia and …

Protein misfolding and aggregation: Mechanism, factors and detection

SK Chaturvedi, MK Siddiqi, P Alam, RH Khan - Process Biochemistry, 2016 - Elsevier
Amyloidogenic diseases are characterised by the formation of amyloid aggregates inside or
outside the cell. Amyloid-associated human diseases include Alzheimer's disease …

Performance of Eversa Transform 2.0 Lipase in Ester Production Using Babassu Oil (Orbignya sp.) and Tucuman Oil (Astrocaryum vulgar): A Comparative Study between Liquid and …

J Brandão Júnior, JG Andrade do Nascimento… - Catalysts, 2023 - mdpi.com
In this study, biodiesel was produced through the enzymatic esterification of vegetable oils
from two common Brazilian palm trees: babassu and tucuman. The oils were hydrolyzed by …

Modulation of amyloid protein fibrillation by synthetic polymers: Recent advances in the context of neurodegenerative diseases

P Ghosh, P De - ACS Applied Bio Materials, 2020 - ACS Publications
Protein misfolding and aggregation have attracted immense research interests due to their
connection with an array of degenerative diseases including neurodegenerative disorders …

Ascorbic acid inhibits human insulin aggregation and protects against amyloid induced cytotoxicity

P Alam, AZ Beg, MK Siddiqi, SK Chaturvedi… - Archives of biochemistry …, 2017 - Elsevier
Protein aggregation into oligomers and fibrils are associated with many human
pathophysiologies. Compounds that modulate protein aggregation and interact with …

Immobilization of lipase onto novel constructed polydopamine grafted multiwalled carbon nanotube impregnated with magnetic cobalt and its application in synthesis …

S Asmat, AH Anwer, Q Husain - International journal of biological …, 2019 - Elsevier
Surface modification of multiwalled carbon nanotubes (MWCNTs) could enhance the
features of the nanomaterial as carrier for enzyme immobilization. In this strategy, magnetic …

Vitamin B12 offers neuronal cell protection by inhibiting Aβ-42 amyloid fibrillation

P Alam, MK Siddiqi, SK Chaturvedi, M Zaman… - International journal of …, 2017 - Elsevier
Protein misfolding and aggregation has been implicated as the cause of more than 20
diseases in humans such as Alzheimer's and Parkinson's and systemic amyloidosis …