Mendelian randomization (MR) is a term that applies to the use of genetic variation to
address causal questions about how modifiable exposures influence different outcomes …

Inverse‐variance weighted two‐sample Mendelian randomization (IVW‐MR) is the most
widely used approach that utilizes genome‐wide association studies (GWAS) summary …

Importance The notion that caffeine increases the risk of cardiac arrhythmias is common.
However, evidence that the consumption of caffeinated products increases the risk of …

Dietary factors are assumed to play an important role in cancer risk, apparent in consensus
recommendations for cancer prevention that promote nutritional changes. However, the …

This study aims to evaluate the causal association of blood pressure (BP) with
cardiovascular diseases (CVDs). Two-sample Mendelian randomization was performed …

Background Insomnia is common and associated with adverse pregnancy and perinatal
outcomes in observational studies. However, those associations could be vulnerable to …

Background Insomnia symptoms are widespread in the population and might have effects
on many chronic conditions and their risk factors but previous research has focused on …

Abstract Background and Aims Smoking increases the risk of severe COVID‐19, but whether
lung function or chronic obstructive pulmonary disease (COPD) mediate the underlying …

OBJECTIVE To examine the effects of sleep traits on glycated hemoglobin (HbA1c).
RESEARCH DESIGN AND METHODS This study triangulated evidence across multivariable …

This study aimed to investigate the causal risk factors for intervertebral disc disorders (IVDD)
to help establish prevention strategies for IVDD‐related diseases. We performed two …