It is now recognized that contracting skeletal muscle may synthesize and release interleukin-
6 (IL-6) into the interstitium as well as into the systemic circulation in response to a bout of …

Alternative splicing is one of the most important mechanisms to generate a large number of
mRNA and protein isoforms from the surprisingly low number of human genes. Unlike …

Abstract Interleukin‐6 (IL‐6) is a multifunctional cytokine that plays a central role in host
defense due to its wide range of immune and hematopoietic activities and its potent ability to …

В обзоре представлен анализ данных литературы, касающихся роли полиморфизма и
экспрессии генов цитокиновой сети в формировании патологического процесса …

There is a universally recognized need to identify new, reliable markers of inflammation that
can aid in the rapid diagnosis of orthopaedic joint prosthesis infections (OJP-Is). Since …

Influenza virus, the causative agent of the common flu, is a worldwide health problem with
significant economic consequences. Studies of influenza virus biology have revealed …

The achievement of keratinocyte gene therapy in clinical practice requires fundamental
experiments using human keratinocytes or skin. We have recently demonstrated that the in …

Background: Until the advent of T cell check point inhibitors standard second-line therapy for
patients with metastatic urothelial cancer (mUC) was undefined. Histone deacetylase …

Abstract Interleukin‐6 (IL‐6) is produced at high levels by renal cell carcinoma cell lines. The
molecular mechanisms involved in its possible role as an autocrine growth factor were …

Amyotrophic lateral sclerosis (ALS) is a fatal movement disorder involving degeneration of
motor neurons through dysfunction of the RNA-binding protein TDP-43. Pericytes, the …