Actinobacillus pleuropneumoniae is the etiological agent of porcine pleuropneumonia, a
respiratory disease leading to severe economic losses in the swine industry. The most …

Pathogenic microorganisms exploit host metabolism for sustained survival by rewiring its
metabolic interactions. Therefore, several metabolic changes are induced in both pathogen …

Klebsiella pneumoniae is a human gut communal organism and notorious opportunistic
pathogen. The relative high burden of asymptomatic colonization by K. pneumoniae is often …

Enrichment methodologies enable the analysis of minor members in multi-species
transcriptomic data. We compared the standard enrichment of bacterial and eukaryotic …

Identifying the direct target genes of response regulators (RRs) of a bacterial two-component
system (TCS) is critical to understand the roles of TCS in bacterial environmental adaption …

Excessive cytokine production is an important component of the acute respiratory distress
syndrome and multiple organ failure. Pneumonia can lead to an overexpression of …

Nitrate metabolism is an adaptation mechanism used by many bacteria for survival in
anaerobic environments. As a by-product of inflammation, nitrate is used by the intestinal …

ABSTRACT Pasteurella multocida (P. multocida), a causative agent of fowl cholera, is an
important pathogen in the poultry industry. In the present study, we found that the inactivated …

Actinobacillus pleuropneumoniae (App) is the causative agent of porcine pleuropneumonia.
Although App produces several virulence factors, Apx toxins, the primary App virulence …

Actinobacillus pleuropneumoniae is the cause of porcine pleuropneumonia, for which the
mortality rate is high. Host peripheral blood is a body site for the immune clearance of …