Cholesterol is an essential structural component of membranes that contributes to
membrane integrity and fluidity. Cholesterol homeostasis plays a critical role in the …

While the central nervous system compromises 2% of our body weight, it harbors up to 25%
of the body's cholesterol. Cholesterol levels in the brain are tightly regulated for …

Cholesterol is dynamically transported among organelles, which is essential for multiple
cellular functions. However, the mechanism underlying intracellular cholesterol transport …

Present review article highlights various cardiovascular risk prediction biomarkers by
incorporating both traditional risk factors to be used as diagnostic markers and recent …

The role of brain cholesterol metabolism in Alzheimer's disease (AD) remains unclear.
Peripheral and brain cholesterol levels are largely independent due to the impermeability of …

Membrane lipids are essential for biological functions ranging from membrane trafficking to
signal transduction. The composition of lipid membranes influences their organization and …

Triacylglycerols are quantitatively the most important storage form of energy for eukaryotic
cells. Acyl CoA: diacylglycerol acyltransferase (DGAT, EC 2.3. 1.20) catalyzes the terminal …

Oxygenated derivatives of cholesterol (oxysterols) present a remarkably diverse profile of
biological activities, including effects on sphingolipid metabolism, platelet aggregation …

Oxysterols are present in human atherosclerotic plaque and are suggested to play an active
role in plaque development. Moreover, the oxysterol: cholesterol ratio in plaque is much …

Conflict of interest: No conflict of interest has been declared. Nonstandard abbreviations
used: free cholesterol (FC); acylcoenzyme A: cholesterol acyltransferase (ACAT); cholesteryl …