Next-generation sequencing (NGS) technologies have become increasingly available for
use in the clinical microbiology diagnostic environment. There are three main applications of …

Clinical microbiology has long relied on growing bacteria in culture to determine
antimicrobial susceptibility profiles, but the use of whole-genome sequencing for antibiotic …

Antimicrobial resistance (AMR) is one of the most important health threats globally. The
ability to accurately identify resistant bacterial isolates and the individual antimicrobial …

Antimicrobial resistance (AMR) is a major public health problem that requires publicly
available tools for rapid analysis. To identify AMR genes in whole-genome sequences, the …

Outbreaks of multidrug-resistant bacteria present a frequent threat to vulnerable patient
populations in hospitals around the world. Intensive care unit (ICU) patients are particularly …

Lactobacillus species are widely used as probiotics and starter cultures for a variety of foods,
supported by a long history of safe usage. Although more than 35 species meet the …

The rapid development of next-generation sequencing (NGS) technology, including
advances in sequencing chemistry, sequencing technologies, bioinformatics, and data …

Rapid advances in DNA sequencing technology (“next-generation sequencing”) have
inspired optimism about the potential of human genomics for “precision medicine.” …

Laboratory-based in vitro antimicrobial susceptibility testing is the foundation for guiding anti-
infective therapy and monitoring antimicrobial resistance trends. We used whole-genome …

Objectives The introduction of metagenomic sequencing to diagnostic microbiology has
been hampered by slowness, cost and complexity. We explored whether MinION nanopore …