Old World Vipers—a review about snake venom proteomics of Viperinae and their variations
Fine-tuned by millions of years of evolution, snake venoms have frightened but also
fascinated humanity and nowadays they constitute potential resources for drug …
fascinated humanity and nowadays they constitute potential resources for drug …
Advances in the therapeutic application of small-molecule inhibitors and repurposed drugs against snakebite: Miniperspective
U Puzari, PA Fernandes… - Journal of Medicinal …, 2021 - ACS Publications
The World Health Organization has declared snakebite as a neglected tropical disease.
Antivenom administration is the sole therapy against venomous snakebite; however, several …
Antivenom administration is the sole therapy against venomous snakebite; however, several …
Varespladib (LY315920) neutralises phospholipase A2 mediated prothrombinase-inhibition induced by Bitis snake venoms
NJ Youngman, A Walker, A Naude, K Coster… - … and Physiology Part C …, 2020 - Elsevier
Anticoagulant toxicity is a common function of venoms produced by species within the Bitis
genus. Potent inhibition of the prothrombinase complex is an identified mechanism of action …
genus. Potent inhibition of the prothrombinase complex is an identified mechanism of action …
Anticoagulant activity of black snake (Elapidae: Pseudechis) venoms: Mechanisms, potency, and antivenom efficacy
Abstract Venoms from Pseudechis species (Australian black snakes) within the Elapidae
family are rich in anticoagulant PLA 2 toxins, with the exception of one species (P …
family are rich in anticoagulant PLA 2 toxins, with the exception of one species (P …
Venom-induced blood disturbances by palearctic viperid snakes, and their relative neutralization by antivenoms and enzyme-inhibitors
Palearctic vipers are medically significant snakes in the genera Daboia, Macrovipera,
Montivipera, and Vipera which occur throughout Europe, Central Asia, Near and Middle …
Montivipera, and Vipera which occur throughout Europe, Central Asia, Near and Middle …
A clot twist: extreme variation in coagulotoxicity mechanisms in Mexican neotropical rattlesnake venoms
Rattlesnakes are a diverse clade of pit vipers (snake family Viperidae, subfamily Crotalinae)
that consists of numerous medically significant species. We used validated in vitro assays …
that consists of numerous medically significant species. We used validated in vitro assays …
Children and snakebite: snake venom effects on adult and paediatric plasma
Snakebite is a globally neglected tropical disease, with coagulation disturbances being the
primary pathology of many deadly snake venoms. Age-related differences in human plasma …
primary pathology of many deadly snake venoms. Age-related differences in human plasma …
Clinical implications of differential procoagulant toxicity of the Palearctic viperid genus Macrovipera, and the relative neutralization efficacy of antivenoms and enzyme …
Species within the viperid genus Macrovipera are some of the most dangerous snakes in the
Eurasian region, injecting copious amounts of potent venom. Despite their medical …
Eurasian region, injecting copious amounts of potent venom. Despite their medical …
Fibrinogenolytic potential of venoms of medically important Brazilian snakes
One of the main clinical manifestations presented by victims of snake bite envenoming are
coagulation disorders. Considering that fibrinogen is a key molecule for crosslinked fibrin …
coagulation disorders. Considering that fibrinogen is a key molecule for crosslinked fibrin …
Compendium of medically important snakes, venom activity and clinical presentations in Ghana
Background Snake bite envenoming (SBE) is one neglected tropical disease that has not
received the needed attention. The sequelae of burdensome disability and mortality impact …
received the needed attention. The sequelae of burdensome disability and mortality impact …