The multifunctional membrane glycoprotein CD36 is expressed in different types of cells and
plays a key regulatory role in cellular lipid metabolism, especially in cardiac muscle. CD36 …

The widely expressed transmembrane glycoprotein, cluster of differentiation 36 (CD36), a
scavenger receptor class B protein (SR-B2), serves many functions in lipid metabolism and …

CD36, also known as the scavenger receptor B2, is a multifunctional receptor widely
expressed in various organs. CD36 plays a crucial role in the uptake of long-chain fatty …

Lipid uptake and metabolism are central to the function of organs such as heart, skeletal
muscle, and adipose tissue. Although most heart energy derives from fatty acids (FAs) …

Abstract The vacuolar H+-ATPases (V-ATPases) are essential, ATP-dependent proton
pumps present in a variety of eukaryotic cellular membranes. Intracellularly, V-ATPase …

The emerging central role of CD36 in cellular lipid homeostasis and recently obtained
molecular insight in the interplay among metabolic substrates indicate the applicability of …

Diabetes is a major risk factor for cardiovascular diseases, including diabetic
cardiomyopathy, atherosclerosis, myocardial infarction, and heart failure. As cardiovascular …

Insulin receptors are highly expressed in the heart and vasculature. Insulin signaling
regulates cardiac growth, survival, substrate uptake, utilization, and mitochondrial …

Luminal pH and the distinctive distribution of phosphatidylinositol phosphate (PIP) lipids are
central identifying features of organelles in all eukaryotic cells that are also critical for …

Human pluripotent stem cell (hPSC) technology has offered nearly infinite opportunities to
model all kinds of human diseases in vitro. Cardiomyocytes derived from hPSCs have …