Alpinetin: a review of its pharmacology and pharmacokinetics

G Zhao, Y Tong, F Luan, W Zhu, C Zhan… - Frontiers in …, 2022 - frontiersin.org
Flavonoids isolated from medicinal herbs have been utilized as valuable health-care agents
due to their virous biological applications. Alpinetin is a natural flavonoid that emerges in …

[HTML][HTML] Solubilization techniques used for poorly water-soluble drugs

B **e, Y Liu, X Li, P Yang, W He - Acta Pharmaceutica Sinica B, 2024 - Elsevier
Currently, about 40% of approved drugs and nearly 90% of drug candidates are poorly
water-soluble drugs. Low solubility reduces the likelihood that these drugs can be effectively …

Amidated Pluronic Decorated Muco-Penetrating Self-Nano Emulsifying Drug Delivery System (SNEDDS) for Improved Anti-Salmonella typhi Potential

R Arshad, MS Arshad, TA Tabish, SNH Shah, S Afzal… - Pharmaceutics, 2022 - mdpi.com
The enteric system residing notorious Salmonella typhimurium (S. typhi) is an intracellular,
food-borne, and zoonotic pathogen causing typhoid fever. Typhoid fever is one of the …

Reduced the food effect and enhanced the oral bioavailability of ivacaftor by self-nanoemulsifying drug delivery system (SNEDDS) using a new oil phase

Y Miao, S Zhao, J Zuo, J Sun… - Drug Design, Development …, 2022 - Taylor & Francis
Purpose The purpose of this work was to develop an ivacaftor self-nanoemulsion drug
delivery system (IVA-SNEDDS) using the newly developed double headed miscellaneous …

Multivariate data analysis and central composite design-oriented optimization of solid carriers for formulation of curcumin-loaded solid SNEDDS: Dissolution and …

L Corrie, J Kaur, A Awasthi, S Vishwas, M Gulati… - Pharmaceutics, 2022 - mdpi.com
The study was initiated with two major purposes: investigating the role of isomalt (GIQ9) as a
pharmaceutical carrier for solid self-nanoemulsifying drug delivery systems (S-SNEDDSs) …

Gastroretentive Sustained-Release Tablets Combined with a Solid Self-Micro-Emulsifying Drug Delivery System Adsorbed onto Fujicalin®

Y Omachi - AAPS PharmSciTech, 2022 - Springer
Gastroretentive drug delivery systems (GRDDS) get retained in the stomach for a long time,
thus facilitating the absorption of drugs in the upper gastrointestinal tract. However, drugs …

Olive oil and castor oil-based self-nanoemulsifying drug delivery system of flurbiprofen can relieve peripheral pain and inflammation through reduction of oxidative …

M Basar, MI Khan, MF Akhtar, F Anwar, A Saleem… - …, 2025 - Springer
Flurbiprofen (FBP) is poorly water-soluble BCS class II drug with anti-inflammatory and
analgesic effects, used to treat arthritis and degenerative joint diseases. This study was …

[PDF][PDF] Modifying Fraction Extracted From Sesewanua (Clerodendrum Fragrans Wild) Leaves In Snedds Preparations: Characterization And Bioavailability Test

Z SAPIUN, AK IMRAN, A ASWAD, MU NUR… - Int J App …, 2024 - academia.edu
Objective: This study aimed to determine the effect of compound modification using acyl
chloride derivatives on n-hexane: ethyl acetate fraction of sesewanua leaves, focusing on …

Responding to Hitch in Fighting Mycobacterium Tuberculosis Through Arginine Multi Functionalized Mucoadhesive SNEDDS of Rifampicin

S Saeed, M Farooq, R Arshad, S Adnan… - Macromolecular …, 2024 - Wiley Online Library
The study aimed to develop thiolated pluronic‐based self‐emulsifying drug delivery system
(SNEDDS) targeted delivery of Rifampicin coated by arginine for enhanced drug loading …

Design and Evaluation of Ginkgolides Gastric Floating Controlled Release Tablets Based on Solid Supersaturated Self-nanoemulsifying

K Zheng, J Zhao, Q Wang, Y Zhao, H Yang, X Yang… - AAPS …, 2023 - Springer
Ginkgolides are receptor antagonist of platelet activating factor with great clinical prospect,
but its application is limited by its low solubility, short half-life and poor alkaline environment …