Renal cell carcinoma (RCC) refers to renal-epithelial cancer, which represents over 90% of
kidney cancer and is a cause for cancer related deaths in the world. Studies suggested …

Characterised by high intra‐and inter‐tumor heterogeneity, metastatic renal cell carcinoma
(RCC) is resistant to chemo‐and radiotherapy. Therefore, the development of new …

Aims: Several studies have demonstrated administration of mesenchymal stem cells (MSC)
could reverse kidney injury by paracrine mechanisms rather than by MSC …

Cancers from sun-exposed skin accumulate" driver" mutations, causally implicated in
oncogenesis. Because errors incorporated during translesion synthesis (TLS) opposite UV …

The cell signaling factors EGFR, EphA2, and Ephexin1 are associated with lung and
colorectal cancer and play an important role in tumorigenesis. Although the respective …

2D culture as a model for drug testing often turns to be clinically futile. Therefore, 3D cultures
(3Ds) show potential to better model responses to drugs observed in vivo. In preliminary …

Cancer cell lines have contributed immensely in understanding the complex physiology of
cancers. They are excellent material for studies as they offer homogenous samples without …

Abstract Aims Micro‐vesicles (MVs) from bone mesenchymal stem cells (MSCs) have been
shown to contribute to the recovery of damaged kidney. The aims of the present study are to …

The cancer stem cell (CSC) model has recently been approached also in renal cell
carcinoma (RCC). A few populations of putative renal tumor-initiating cells (TICs) were …

Deficiency in several of the classical human RAD51 paralogs [RAD51B, RAD51C, RAD51D,
XRCC2 and XRCC3] is associated with cancer predisposition and Fanconi anemia. To …