Medicinal inorganic chemistry offers additional opportunities for the design of therapeutic
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …

Radiometals comprise many useful radioactive isotopes of various metallic elements. When
properly harnessed, these have valuable emission properties that can be used for …

Imidazole ring is an important five‐membered aromatic heterocycle widely present in natural
products and synthetic molecules. The unique structural feature of imidazole ring with …

Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems …

Our desire to understand how the individual molecules that make up cells organize, interact,
and communicate to form living systems has led to the burgeoning field of chemical biology …

Copper is an important trace element that is required for essential enzymes. However, due
to its redox activity, copper can also lead to the generation of toxic reactive oxygen species …

Nuclear medicine is composed of two complementary areas, imaging and therapy. Positron
emission tomography (PET) and single-photon imaging, including single-photon emission …

Approximately one third of the human proteome contains metal cations, either in the form of
cofactors with catalytic functions or as structural support elements. 1, 2 To guarantee a …

Background Recent advances in nanotechnology have offered new hope for cancer
detection, prevention, and treatment. Nanomedicine, a term for the application of …

Macrocyclic chelators can form highly stable complexes with transition metals and
lanthanides. In this review, the recent advances towards biomedical applications of …