In 1925, 5-methylcytosine was first reported in bacteria. However, its biological importance
was not intuitive for several decades. After this initial lag, the ubiquitous presence of this …

DNA methylation is a conserved epigenetic modification that is important for gene regulation
and genome stability. Aberrant patterns of DNA methylation can lead to plant developmental …

A contribution of DNA methylation to defense against invading nucleic acids and
maintenance of genome integrity is uncontested; however, our understanding of the extent …

Silencing of transposable elements (TEs) is established by small RNA-directed DNA
methylation (RdDM). Maintenance of silencing is then based on a combination of RdDM and …

Plant intra-individual and inter-individual variation can be determined by the epigenome, a
set of covalent modifications of DNA and chromatin that can alter genome structure and …

Methylation of DNA and of histone 3 at Lys 9 (H3K9) are highly correlated with gene
silencing in eukaryotes from fungi to humans. Both of these epigenetic marks need to be …

DNA methylation is a major epigenetic mark with important roles in genetic regulation.
Methylated cytosines are found primarily at CpG dinucleotides, but are also found at non …

Background DNA methylation is an important feature of plant epigenomes, involved in the
formation of heterochromatin and affecting gene expression. Extensive variation of DNA …

Genetically Modified Organism-Free RNA Interference: Exogenous Application of RNA Molecules
in Plants1 [OPEN] | Plant Physiology | Oxford Academic Skip to Main Content Advertisement …

DNA methylation is an important epigenetic modification involved in gene regulation and
transposable element silencing. Changes in DNA methylation can be heritable and, thus …