A fundamental feature of cellular growth is that total protein and RNA amounts increase with
cell size to keep concentrations approximately constant. A key component of this is that …

The nuclear envelope (NE) is a protective barrier to the genome, yet its membranes undergo
highly dynamic remodeling processes that are necessary for cell growth and maintenance …

As cells grow, the size and number of their internal organelles increase in order to keep up
with increased metabolic requirements. Abnormal size of organelles is a hallmark of cancer …

The size of the nucleus scales robustly with cell size so that the nuclear-to-cell volume ratio
(N/C ratio) is maintained during cell growth in many cell types. The mechanism responsible …

High-resolution and rapid imaging of host cell ultrastructure can generate insights toward
viral disease mechanism, for example for a severe acute respiratory syndrome coronavirus …

Nuclear size plays pivotal roles in gene expression, embryo development, and disease. A
central hypothesis in organisms ranging from yeast to vertebrates is that nuclear size scales …

Understanding how the integrity of the nuclear membranes is protected against internal and
external stresses is an emergent challenge. Work reviewed here investigated the …

Upon infection, viruses hijack the cell machinery and remodel host cell structures to utilize
them for viral proliferation. Since viruses are about a thousand times smaller than their host …

During early embryogenesis, as cells divide in the develo** embryo, the size of
intracellular organelles generally decreases to scale with the decrease in overall cell size …

The packing and confinement of macromolecules in the cytoplasm and nucleoplasm has
profound implications for cellular biochemistry. How intracellular density distributions vary …