Epilepsy is one of the most common neurological disorders. Although epilepsy can be
idiopathic, it is estimated that up to 50% of all epilepsy cases are initiated by neurological …

Acute brain insults, such as traumatic brain injury, status epilepticus, or stroke are common
etiologies for the development of epilepsy, including temporal lobe epilepsy (TLE), which is …

Ultrasound-driven bioelectronics could offer a wireless scheme with sustainable power
supply; however, current ultrasound implantable systems present critical challenges in …

Infusion of the K+ channel blocker 4-aminopyridine in the hippocampus induces the release
of glutamate, as well as seizures and neurodegeneration. Since an imbalance between …

During postnatal development of CA1 pyramidal neurons, GABAergic synapses are
excitatory and established prior to glutamatergic synapses. As interneurons are generated …

Not only are GABA A receptors activated transiently by GABA released at synapses, but high
affinity, extrasynaptic GABA A receptors are also activated by ambient, extracellular GABA …

Glutamate (GLU) and γ-aminobutyric acid (GABA) are the major excitatory (E) and inhibitory
(I) neurotransmitters in the brain, respectively. Dysregulation of the E/I ratio is associated …

In spite of several studies showing specific physiological functions of changes in the
extracellular level of the major excitatory and inhibitory transmitters, Glu and GABA within …

Because of their high energetic demand, neurons within the mammalian central nervous
system are extremely sensitive to changes in partial pressure of oxygen. Faced with acute …

Early cognitive deficit characteristic of early Alzheimer's disease seems to be produced by
the soluble forms of β‐amyloid protein. Such cognitive deficit correlates with neuronal …