Systematic exploration of Escherichia coli phage–host interactions with the BASEL phage collection

E Maffei, A Shaidullina, M Burkolter, Y Heyer… - PLoS …, 2021 - journals.plos.org
Bacteriophages, the viruses infecting bacteria, hold great potential for the treatment of
multidrug-resistant bacterial infections and other applications due to their unparalleled …

Phage Paride can kill dormant, antibiotic-tolerant cells of Pseudomonas aeruginosa by direct lytic replication

E Maffei, AK Woischnig, MR Burkolter, Y Heyer… - Nature …, 2024 - nature.com
Bacteriophages are ubiquitous viral predators that have primarily been studied using fast-
growing laboratory cultures of their bacterial hosts. However, microbial life in nature is …

[HTML][HTML] Bacteriophage therapy: recent developments and applications of a renaissant weapon

B Fathima, AC Archer - Research in microbiology, 2021 - Elsevier
Antimicrobial resistance is a global health problem and one of the leading concerns in
healthcare sector. Bacteriophages are antibacterial agents ubiquitous in nature. With …

Challenges for the application of bacteriophages as effective antibacterial agents in the food industry

J Li, F Zhao, W Zhan, Z Li, L Zou… - Journal of the Science of …, 2022 - Wiley Online Library
Food contamination caused by foodborne pathogens is one of the most important concerns
in public health worldwide, and accounts for a significant portion of food loss every year. The …

Map** the functional landscape of the receptor binding domain of T7 bacteriophage by deep mutational scanning

P Huss, A Meger, M Leander, K Nishikawa, S Raman - Elife, 2021 - elifesciences.org
The interaction between a bacteriophage and its host is mediated by the phage's receptor
binding protein (RBP). Despite its fundamental role in governing phage activity and host …

The microbiome in pancreatic cancer-implications for diagnosis and precision bacteriophage therapy for this low survival disease

M Kabwe, S Dashper, J Tucci - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
While the mortality rates for many cancers have decreased due to improved detection and
treatments, that of pancreatic cancer remains stubbornly high. The microbiome is an …

Hypoxia Increases the Tempo of Phage Resistance and Mutational Bottlenecking of Pseudomonas aeruginosa

AR Schumann, AD Sue, DR Roach - Frontiers in Microbiology, 2022 - frontiersin.org
Viruses that infect bacteria (ie, phages) are abundant and widespread in the human body,
and new anti-infective approaches such as phage therapy are essential for the future of …

Phenotypic Characterization and Whole-Genome Analysis of a Novel Bacteriophage HCF1 Infecting Citrobacter amalonaticus and C. freundii

P Kumar, MK Meghvansi, DV Kamboj - Frontiers in microbiology, 2021 - frontiersin.org
Citrobacter species often occur in sewage, food, soil, wastewater, and in the intestinal tract
of animals and humans. Citrobacter spp. cause urinary tract infections (UTIs) and infantile …

Isolation and Characterization of Lytic Bacteriophages Targeting Diverse Enterobacter spp. Clinical Isolates

AG Finney, JM Perry, DR Evans… - Therapy, Applications …, 2022 - liebertpub.com
Background: Enterobacter spp. are opportunistic pathogens that cause nosocomial
infections. Bacteriophages could be used to treat antibiotic-resistant Enterobacter infections …

Cooperation between physiological defenses and immune resistance produces asymptomatic carriage of a lethal bacterial pathogen

GY Chen, NR Thorup, AJ Miller, YC Li, JS Ayres - Science Advances, 2023 - science.org
Animals evolved two defense strategies to survive infections. Antagonistic strategies include
immune resistance mechanisms that operate to kill invading pathogens. Cooperative or …