Late embryogenesis abundant (LEA) proteins are extremely hydrophilic proteins that were
first identified in land plants. Intracellular accumulation is tightly correlated with acquisition of …

Disordered proteins have long been known to help mediate tolerance to different abiotic
stresses including freezing, osmotic stress, high temperatures, and desiccation in a diverse …

Tardigrades are microscopic animals that survive a remarkable array of stresses, including
desiccation. How tardigrades survive desiccation has remained a mystery for more than 250 …

Lipid-like nanoparticles (LLNs) have been extensively explored for messenger RNA (mRNA)
delivery in various biomedical applications. However, the long-term storage of these …

The broadest clinical application of siRNA therapeutics will be facilitated by drug-loaded
delivery systems that maintain stability and potency for long times under ambient conditions …

Tardigrada, a phylum of meiofaunal organisms, have been at the center of discussions of the
evolution of Metazoa, the biology of survival in extreme environments, and the role of …

Tardigrades are microscopic animals renowned for their ability to survive extreme
desiccation. Unlike many desiccation-tolerant organisms that accumulate high levels of the …

Extremotolerant organisms and industry exploit sugars as desiccation protectants, with
trehalose being widely used by both. How sugars, in general, and the hydrolytically stable …

Tardigrades are able to tolerate almost complete dehydration by entering a reversible
ametabolic state called anhydrobiosis and resume their animation upon rehydration …

Water is critical for the survival of most cells and organisms. Remarkably, a small number of
multicellular animals are able to survive nearly complete drying. The phenomenon of …