MASLD: a systemic metabolic disorder with cardiovascular and malignant complications
Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common chronic
liver disease globally and is currently estimated to affect up to 38% of the global adult …
liver disease globally and is currently estimated to affect up to 38% of the global adult …
Macrophages and T cells in metabolic disorder-associated cancers
Cancer and metabolic disorders have emerged as major global health challenges, reaching
epidemic levels in recent decades. Often viewed as separate issues, metabolic disorders …
epidemic levels in recent decades. Often viewed as separate issues, metabolic disorders …
Dendritic cell maturation in cancer
Dendritic cells (DCs) are specialized antigen-presenting cells that are present at low
abundance in the circulation and tissues; they serve as crucial immune sentinels by …
abundance in the circulation and tissues; they serve as crucial immune sentinels by …
Direct degradation and stabilization of proteins: New horizons in treatment of nonalcoholic steatohepatitis
Y Wang, J Zheng, Y Long, W Wu, Y Zhu - Biochemical Pharmacology, 2024 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is featured with excessive hepatic lipid
accumulation and its global prevalence is soaring. Nonalcoholic steatohepatitis (NASH), the …
accumulation and its global prevalence is soaring. Nonalcoholic steatohepatitis (NASH), the …
Derlin-1 promotes diet-induced non-alcoholic fatty liver disease via increasing RIPK3-mediated necroptosis
T Wang, D Wang, G Kuang, X Gong, L Zhang… - Free Radical Biology …, 2024 - Elsevier
Background & aims Unrestricted endoplasmic reticulum (ER) stress and the continuous
activation of ER associated protein degradation (ERAD) pathway might lead to the …
activation of ER associated protein degradation (ERAD) pathway might lead to the …
Oligonucleotide therapies for nonalcoholic steatohepatitis
S Li, F **ong, S Zhang, J Liu, G Gao, J **e… - … Therapy-Nucleic Acids, 2024 - cell.com
Nonalcoholic Steatohepatitis represents a severe disease subtype of nonalcoholic fatty liver
disease which is thought to be highly associated with systemic metabolic abnormalities. It is …
disease which is thought to be highly associated with systemic metabolic abnormalities. It is …
The double-edged effects of IL-6 in liver regeneration, aging, inflammation, and diseases
MJ Wang, HL Zhang, F Chen, XJ Guo, QG Liu… - … Hematology & Oncology, 2024 - Springer
Abstract Interleukin-6 (IL-6) is a pleiotropic cytokine and exerts its complex biological
functions mainly through three different signal modes, called cis-, trans-, and cluster …
functions mainly through three different signal modes, called cis-, trans-, and cluster …
Exogenous hydrogen sulfide improves non-alcoholic fatty liver disease by inhibiting endoplasmic reticulum stress/NLRP3 inflammasome pathway
X Fu, Q Zhang, Y Chen, Y Li, H Wang - Molecular and Cellular …, 2025 - Springer
Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease worldwide, and
its exact pathogenesis has not been fully studied. Hydrogen sulfide (H 2 S) is the third gas …
its exact pathogenesis has not been fully studied. Hydrogen sulfide (H 2 S) is the third gas …
Impact of hepatic inflammation and fibrosis on the recurrence and long-term survival of hepatitis B virus-related hepatocellular carcinoma patients after hepatectomy
X Hao, L Xu, X Lan, B Li, H Cai - BMC cancer, 2024 - Springer
Background Underlying liver disease is correlated with hepatocellular carcinoma (HCC)
development in patients with hepatitis B virus (HBV) infection. However, the impact of …
development in patients with hepatitis B virus (HBV) infection. However, the impact of …
Unraveling the underlying pathogenic factors driving nonalcoholic steatohepatitis and hepatocellular carcinoma: an in-depth analysis of prognostically relevant gene …
Y Ni, M Lu, M Li, X Hu, F Li, Y Wang, D Xue - Journal of Translational …, 2024 - Springer
Background Nonalcoholic steatohepatitis (NASH) is a progressive manifestation of
nonalcoholic fatty liver disease (NAFLD) that can lead to fibrosis, cirrhosis, and …
nonalcoholic fatty liver disease (NAFLD) that can lead to fibrosis, cirrhosis, and …