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Learning to be elite: lessons from HIV-1 controllers and animal models on trained innate immunity and virus suppression
S Sugawara, RK Reeves, S Jost - Frontiers in Immunology, 2022 - frontiersin.org
Although antiretroviral therapy (ART) has drastically changed the lives of people living with
human immunodeficiency virus-1 (HIV-1), long-term treatment has been associated with a …
human immunodeficiency virus-1 (HIV-1), long-term treatment has been associated with a …
Actions of retinoic acid in the pathophysiology of HIV infection
N Sidell, MA Kane - Nutrients, 2022 - mdpi.com
The vitamin A metabolite all-trans retinoic acid (RA) plays a key role in tissue homeostasis
and mucosal immunity. RA is produced by gut-associated dendritic cells, which are among …
and mucosal immunity. RA is produced by gut-associated dendritic cells, which are among …
Evolution of T cell responses during measles virus infection and RNA clearance
AN Nelson, N Putnam, D Hauer, VK Baxter… - Scientific reports, 2017 - nature.com
Measles is an acute viral disease associated both with immune suppression and
development of life-long immunity. Clearance of measles virus (MeV) involves rapid …
development of life-long immunity. Clearance of measles virus (MeV) involves rapid …
Hypercytotoxicity and Rapid Loss of NKp44+ Innate Lymphoid Cells during Acute SIV Infection
H Li, LE Richert-Spuhler, TI Evans, J Gillis… - PLoS …, 2014 - journals.plos.org
HIV/SIV infections break down the integrity of the gastrointestinal mucosa and lead to
chronic immune activation and associated disease progression. Innate lymphoid cells …
chronic immune activation and associated disease progression. Innate lymphoid cells …
Mucosal regulatory T cells and T helper 17 cells in HIV-associated immune activation
Residual mucosal inflammation along with chronic systemic immune activation is an
important feature in individuals infected with human immunodeficiency virus (HIV), and has …
important feature in individuals infected with human immunodeficiency virus (HIV), and has …
FoxP3+ CD8 T-cells in acute HIV infection and following early antiretroviral therapy initiation
Objectives Besides CD4 regulatory T-cells (Tregs), immunosuppressor FoxP3+ CD8 T-cells
are emerging as an important subset of Tregs, which contribute to immune dysfunction and …
are emerging as an important subset of Tregs, which contribute to immune dysfunction and …
[HTML][HTML] Effective innate immune response in natural HIV-1 controllers. Can mimicking lead to novel preventive and cure strategies against HIV-1?
M Calvet-Mirabent, E Martín-Gayo - Current Opinion in HIV and …, 2022 - journals.lww.com
Current Opinion in HIV and AIDS Log in or Register Subscribe to journalSubscribe Get new
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In vivo administration of a JAK3 inhibitor during acute SIV infection leads to significant increases in viral load during chronic infection
Y Takahashi, SN Byrareddy, C Albrecht… - PLoS …, 2014 - journals.plos.org
The studies reported herein are the first to document the effect of the in vivo administration of
a JAK3 inhibitor for defining the potential role of NK cells during acute SIV infection of a …
a JAK3 inhibitor for defining the potential role of NK cells during acute SIV infection of a …
Mucosal T helper 17 and T regulatory cell homeostasis correlate with acute simian immunodeficiency virus viremia and responsiveness to antiretroviral therapy in …
MA O'Connor, PV Munson, HC Tunggal… - AIDS research and …, 2019 - liebertpub.com
Depletion of gut T helper 17 (Th17) cells during HIV infection leads to decreased mucosal
integrity and increased disease progression. Conversely, T regulatory (Treg) cells may …
integrity and increased disease progression. Conversely, T regulatory (Treg) cells may …
In Vivo Administration of a JAK3 Inhibitor to Chronically SIV Infected Rhesus Macaques Leads to NK Cell Depletion Associated with Transient Modest Increase in …
Y Takahashi, AE Mayne, L Khowawisetsut… - PLoS …, 2013 - journals.plos.org
Innate immune responses are reasoned to play an important role during both acute and
chronic SIV infection and play a deterministic role during the acute stages on the rate of …
chronic SIV infection and play a deterministic role during the acute stages on the rate of …