Hydrogel interfaces for merging humans and machines

H Yuk, J Wu, X Zhao - Nature Reviews Materials, 2022‏ - nature.com
The last few decades have witnessed unprecedented convergence between humans and
machines that closely operate around the human body. Despite these advances, traditional …

Tumor abnormality-oriented nanomedicine design

Q Zhou, J **ang, N Qiu, Y Wang, Y Piao, S Shao… - Chemical …, 2023‏ - ACS Publications
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

[HTML][HTML] Going below and beyond the surface: Microneedle structure, materials, drugs, fabrication, and applications for wound healing and tissue regeneration

S Lyu, Z Dong, X Xu, HP Bei, HY Yuen, CWJ Cheung… - Bioactive materials, 2023‏ - Elsevier
Microneedle, as a novel drug delivery system, has attracted widespread attention due to its
non-invasiveness, painless and simple administration, controllable drug delivery, and …

Responsive biomaterials: optimizing control of cancer immunotherapy

L Xue, AS Thatte, D Mai, RM Haley, N Gong… - Nature Reviews …, 2024‏ - nature.com
Immunotherapy has emerged as an eminent and effective modality in the treatment of
cancer. However, current cancer immunotherapies lack spatial and temporal control …

The fast-growing field of photo-driven theranostics based on aggregation-induced emission

Z Zhang, M Kang, H Tan, N Song, M Li, P **ao… - Chemical Society …, 2022‏ - pubs.rsc.org
Photo-driven theranostics, also known as phototheranostics, relying on the diverse excited-
state energy conversions of theranostic agents upon photoexcitation represents a significant …

To PEGylate or not to PEGylate: Immunological properties of nanomedicine's most popular component, polyethylene glycol and its alternatives

D Shi, D Beasock, A Fessler, J Szebeni… - Advanced drug delivery …, 2022‏ - Elsevier
Polyethylene glycol or PEG has a long history of use in medicine. Many conventional
formulations utilize PEG as either an active ingredient or an excipient. PEG found its use in …

Microneedle biomedical devices

M Zheng, T Sheng, J Yu, Z Gu, C Xu - Nature Reviews Bioengineering, 2024‏ - nature.com
Microneedle (MN) technologies have gained interest for biomedical applications, ranging
from drug delivery to sensing and tissue sampling in skin and internal organs. The …

Recent advances in smart stimuli-responsive biomaterials for bone therapeutics and regeneration

H Wei, J Cui, K Lin, J **e, X Wang - Bone research, 2022‏ - nature.com
Bone defects combined with tumors, infections, or other bone diseases are challenging in
clinical practice. Autologous and allogeneic grafts are two main traditional remedies, but …

Dynamic and reconfigurable materials from reversible network interactions

MJ Webber, MW Tibbitt - Nature Reviews Materials, 2022‏ - nature.com
Polymer materials provide solutions to some of the most pressing environmental,
manufacturing and health-care challenges. Traditional thermoplastic and thermoset …

Nanocarriers address intracellular barriers for efficient drug delivery, overcoming drug resistance, subcellular targeting and controlled release

J Liu, H Cabral, P Mi - Advanced Drug Delivery Reviews, 2024‏ - Elsevier
The cellular barriers are major bottlenecks for bioactive compounds entering into cells to
accomplish their biological functions, which limits their biomedical applications …