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Cognitive impairment caused by hypoxia: from clinical evidences to molecular mechanisms
X Wang, L Cui, X Ji - Metabolic brain disease, 2022 - Springer
Hypoxia is a state of reduced oxygen supply and excessive oxygen consumption. According
to the duration of hypoxic period, it can be classified as acute and chronic hypoxia. Both …
to the duration of hypoxic period, it can be classified as acute and chronic hypoxia. Both …
Mechanism, prevention and treatment of cognitive impairment caused by high altitude exposure
X Chen, J Zhang, Y Lin, Y Li, H Wang, Z Wang… - Frontiers in …, 2023 - frontiersin.org
Hypobaric hypoxia (HH) characteristics induce impaired cognitive function, reduced
concentration, and memory. In recent years, an increasing number of people have migrated …
concentration, and memory. In recent years, an increasing number of people have migrated …
[HTML][HTML] Alterations in the gut microbiota contribute to cognitive impairment induced by the ketogenic diet and hypoxia
CA Olson, AJ Iñiguez, GE Yang, P Fang… - Cell host & …, 2021 - cell.com
Many genetic and environmental factors increase susceptibility to cognitive impairment (CI),
and the gut microbiome is increasingly implicated. However, the identity of gut microbes …
and the gut microbiome is increasingly implicated. However, the identity of gut microbes …
Cordycepin ameliorates acute hypobaric hypoxia induced blood-brain barrier disruption, and cognitive impairment partly by suppressing the TLR4/NF-κB/MMP-9 …
P Liu, L Pan, L Cui, T Li, S Zhao, Y Hu, X Tao… - European Journal of …, 2022 - Elsevier
Background Hypobaric hypoxia exposure leads to brain edema, followed by
neuropsychological disorders. However, the related mechanism and effective treatments are …
neuropsychological disorders. However, the related mechanism and effective treatments are …
[HTML][HTML] Effect of acute normobaric hypoxia exposure on executive functions among young physically active males
M Chroboczek, M Kostrzewa, K Micielska… - Journal of Clinical …, 2021 - mdpi.com
Background: On the one hand, hypoxic exposure may result in progressive brain
metabolism disturbance, causing subsequent cognitive impairments. On the other hand, it …
metabolism disturbance, causing subsequent cognitive impairments. On the other hand, it …
Effect of acetazolamide on visuomotor performance at high altitude in healthy people 40 years of age or older—RCT
Objective Altitude travel is increasingly popular also for middle-aged and older tourists and
professionals. Due to the sensitivity of the central nervous system to hypoxia, altitude …
professionals. Due to the sensitivity of the central nervous system to hypoxia, altitude …
The neuroimmune pathway of high-altitude adaptation: influence of erythrocytes on attention networks through inflammation and the autonomic nervous system
Introduction Many studies have shown that the functional adaptation of immigrants to high-
altitude is closely related to oxygen transport, inflammatory response and autonomic …
altitude is closely related to oxygen transport, inflammatory response and autonomic …
Differential effects of high-altitude exposure on markers of oxidative stress, antioxidant capacity, and iron profiles
CL Rytz, M Pun, JA Mawhinney… - American Journal …, 2022 - journals.physiology.org
High-altitude (HA) exposure may stimulate significant physiological and molecular changes,
resulting in HA-related illnesses. HA may impact oxidative stress, antioxidant capacity, and …
resulting in HA-related illnesses. HA may impact oxidative stress, antioxidant capacity, and …
The Effects of Nocturnal Hypoxemia on Cognitive Performance in Andean Highlanders
EV Young, MA Djokic, EC Heinrich, T Marin… - … Altitude Medicine & …, 2024 - liebertpub.com
Background: Many Andean highlanders exposed to chronic hypoxemia are susceptible to
excessive erythrocytosis (EE) and chronic mountain sickness (CMS). Nocturnal hypoxemia …
excessive erythrocytosis (EE) and chronic mountain sickness (CMS). Nocturnal hypoxemia …
[HTML][HTML] Extravascular lung water and cardiac function assessed by echocardiography in healthy lowlanders during repeated very high-altitude exposure
Background High-altitude pulmonary edema is associated with elevated systolic pulmonary
artery pressure (sPAP) and increased extravascular lung water (EVLW). We investigated …
artery pressure (sPAP) and increased extravascular lung water (EVLW). We investigated …