Caspases are proteolytic enzymes that belong to the cysteine protease family and play a
crucial role in homeostasis and programmed cell death. Caspases have been broadly …

Alzheimer's disease (AD) is a devastating age-related neurodegenerative disorder with an
alarming increasing prevalence. Except for the recently FDA-approved Aducanumab of …

The increasing life expectancy has led to a higher incidence of age-related
neurodegenerative conditions. Within this framework, neuroinflammation emerges as a …

NLRP3 (NOD-like receptor pyrin domain-containing protein 3) is an innate immune sensor
that contributes to the development of different diseases, including monogenic …

Inflammatory bowel disease (IBD) is one of the most common diseases in the
gastrointestinal tract related to aberrant inflammation. Pyroptosis, which is characterized by …

Inflammasomes are intracellular complexes involved in the innate immunity that convert
proIL‐1β and proIL‐18 to mature forms and initiate pyroptosis via cleaving procaspase‐1 …

Acute lung injury and acute respiratory distress syndrome (ALI/ARDS) is characterized by
uncontrolled progressive lung inflammation. Macrophages serve a key role in the …

Recent evidence indicates that exosomes derived from mesenchymal stem cells (MSCs)
confer protective effects against myocardial ischemia/reperfusion (I/R) injury. Exosomes are …

The interaction between lipid nanoparticles (LNPs) and serum proteins, giving rise to a
unique identification in the form of the protein corona, has been shown to be associated with …

Since the introduction of artificial sweeteners (AS) to the North American market in the
1950s, a growing number of epidemiological and animal studies have suggested that AS …