Why do hosts malfunction without microbes? Missing benefits versus evolutionary addiction

TJ Hammer - Trends in Microbiology, 2024 - cell.com
Microbes are widely recognized to be vital to host health. This new consensus rests, in part,
on experiments showing how hosts malfunction when microbes are removed. More and …

Microbial sensing in the intestine

T Wan, Y Wang, K He, S Zhu - Protein & Cell, 2023 - academic.oup.com
The gut microbiota plays a key role in host health and disease, particularly through their
interactions with the immune system. Intestinal homeostasis is dependent on the symbiotic …

Human breastmilk-derived Bifidobacterium longum subsp. infantis CCFM1269 regulates bone formation by the GH/IGF axis through PI3K/AKT pathway

M Ding, B Li, H Chen, D Liang, RP Ross, C Stanton… - Gut …, 2024 - Taylor & Francis
Bifidobacterium longum subsp. infantis is a prevalent member of the gut microbiota of
breastfed infants. In this study, the effects of human breastmilk-derived B. longum subsp …

Malnourished Microbes: Host–Microbiome Interactions in Child Undernutrition

HJ Jones, CD Bourke, JR Swann… - Annual Review of …, 2023 - annualreviews.org
Childhood undernutrition is a major global health burden that is only partially resolved by
nutritional interventions. Both chronic and acute forms of child undernutrition are …

Chemical genetic approaches to dissect microbiota mechanisms in health and disease

X Yang, HC Hang - Science, 2024 - science.org
Advances in genomics, proteomics, and metabolomics have revealed associations between
specific microbiota species in health and disease. However, the precise mechanism (s) of …

Cereal-based fermented foods as microbiota-directed products for improved child nutrition and health in sub-Saharan Africa

M Houngbédji, JS Jespersen… - Critical Reviews in …, 2024 - Taylor & Francis
Several strategies, programs and policies have long been developed and implemented to
alleviate child malnutrition in sub-Saharan African countries. However, stunting and wasting …

Immunogenic molecules associated with gut bacterial cell walls: chemical structures, immune-modulating functions, and mechanisms

R Yin, T Wang, H Dai, J Han, J Sun, N Liu… - Protein & …, 2023 - academic.oup.com
Interactions between gut microbiome and host immune system are fundamental to
maintaining the intestinal mucosal barrier and homeostasis. At the host-gut microbiome …

Symbiotic probiotic communities with multiple targets successfully combat obesity in high-fat-diet-fed mice

D Guo, Y Deng, Q Yang, M Li, X Wang, X Wan, J He… - Gut …, 2024 - Taylor & Francis
Probiotics hold great potential for treating metabolic diseases such as obesity. Given the
complex and multifactorial nature of these diseases, research on probiotic combination with …

Suboptimal refeeding compensates stunting in a mouse model of juvenile malnutrition

JL Thoumas, A Cavaroc, D Sery, F Leulier… - The Journal of …, 2025 - Elsevier
Background Early postnatal life is a critical period of rapid growth in mammals, heavily
reliant on adequate nutrition. Protein-energy malnutrition (PEM) during this window can lead …

The hidden base of the iceberg: gut peptidoglycome dynamics is foundational to its influence on the host

R Wheeler, I Gomperts Boneca - Gut microbes, 2024 - Taylor & Francis
The intestinal microbiota of humans includes a highly diverse range of bacterial species. All
these bacteria possess a cell wall, composed primarily of the macromolecule peptidoglycan …